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Azilsartan

Last updated on 23/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Azilsartan 

CHINESE NAME: 阿齊沙坦

BRAND NAME(S) IN HONG KONG: Edarbi易達標, Edarbyclor 易達妥

(Contains Azilsartan and Chlorthalidone) 

DRUG CLASS: Angiotensin II receptor blocker; Antihypertensive 

USED FOR: High blood pressure 

OTHER DRUGS IN THE SAME CLASS: Candesartan, Eprosartan, Irbesartan, Losartan, Olmesartan, Telmisartan, Valsartan

AVAILABLE DOSAGE FORMS: 40mg, 80mg (tablets)

What is Azilsartan for?

Azilsartan belongs to a class of medications called angiotensin receptor blockers (ARBs), just like Losartan. ARBs block the substances that constrict the blood vessels and hence more blood and oxygen can reach the heart. Azilsartan is therefore commonly used for the management of high blood pressure, especially when medications such as Lisinopril or Ramipril (angiotensin converting enzyme inhibitor) cannot be used.

How to use it?

Azilsartan is given orally as tablets. The initial dose for adults is 40 mg once daily. The dose for patients over 75 years old, at risk of low blood pressure, or with volume or salt depletion may reduce to 20 mg once daily. The dose may be adjusted based on your response. The maximum daily dose is 80 mg once daily.

What are the side effects of Azilsartan?

Common side effects of Azilsartan include diarrhoea, dizziness, headache, high potassium levels, low blood pressure, and kidney impairment. If you have intravascular volume depletion, for example, those taking high-dose other blood pressure-lowering drugs, you may also experience postural hypotension, that is your blood pressure falls when you stand up from sitting or lying down.

Who should not take Azilsartan?

– People with an allergy to Azilsartan or any formulation ingredient
– Patients who are on Aliskiren and with diabetes

Pharmacist Tips:

– Inform your doctor or pharmacist immediately if you know you are pregnant while on this medication.
– Avoid alcohol while you are taking Azilsartan to reduce dizziness.
– If you experience postural hypotension, get up slowly from lying or sitting positions or sit down until you feel better. 

Common dosing schedule:
You can take Azilsartan with or without food. 

Take the first dose at bedtime to avoid dizziness. You can take it at any time of day afterwards. Take the drug at the same time every day.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Azilsartan may interact with:
– Angiotensin-converting enzyme inhibitor, e.g. Captopril, Enalapril
– Heparin
Lithium 
– Nonsteroidal anti-inflammatory drugs, e.g. Ibuprofen, Naproxen
– Other angiotensin II receptor blockers, e.g. Telmisartan, Valsartan
Potassium supplements
Spironolactone

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Azilsartan in Hong Kong?

In Hong Kong, Azilsartan is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Azilsartan in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.