Spironolactone🔊

What is Spironolactone for?

Spironolactone belongs to a class of medications called aldosterone antagonists (or potassium-sparing diuretics). It helps your body to get rid of salt and water more easily and also blocks the activity of male hormones (androgens). It is commonly used for swelling, liver cirrhosis, high blood pressure, high aldosterone level, heart failure with swelling and low potassium level. Spironolactone’s anti-androgen effects can be helpful in women with certain types of acne, excessive male-pattern hair growth (hirsutism), and female pattern hair loss (androgenic alopecia). 

How to use it?

Spironolactone is taken by mouth.

The suggested oral dosages for different uses and age groups are listed below: 

For swelling

Adult 

Take 100 mg once or twice daily.

Child

Usually 1-3 mg/kg/day every 6 to 24 hours. Doses are adjusted according to response.

For liver cirrhosis with swelling

Adult

Take 100 mg daily. Dosage ranges up to 400 mg daily.

Elderly

Start with the lowest effective dose then adjust upward if necessary

For high aldosterone level

Adult

Start with 100-400 mg. The lowest effective dose will be given as a maintenance dose.

Child

Usually 1-3 mg/kg/day every 6 to 24 hours. Doses are adjusted according to response.

Elderly

Start with the lowest effective dose then adjust upward if necessary

For heart failure with swelling

Adult and Elderly

Usually start with 12.5- 25 mg once daily. If 25 mg once daily dose is not tolerated, 25 mg every other day will be given.

For high blood pressure

Adults

Usually start with 25-50 mg daily

For women with acne, hirsutism, or androgenic alopecia

Adults

Usually start with 50-100 mg once or twice daily. Doses are adjusted based on response.

What are the side effects of Spironolactone?

The common side effects of Spironolactone are diarrhea, nausea, and high blood potassium levels. Some less common side effects include irregular menstrual bleeding, erectile dysfunction, high blood glucose level, and enlarged breasts in men.

Where to buy Spironolactone in Hong Kong?

In Hong Kong, Spironolactone is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.