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Enalapril

Last updated on 12/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Enalapril

CHINESE NAME: 依那普利

BRAND NAME(S) IN HONG KONG: Enapril 得控壓, Renitec 悅您定

DRUG CLASS: Antihypertensives

SUB CLASS: Angiotensin-converting enzyme (ACE) inhibitors

USED FOR: High blood pressure, heart failure

AVAILABLE DOSAGE FORMS:
– 2.5 mg, 5 mg, 10 mg, 20 mg (tablets)

What is Enalapril for?

Enalapril belongs to a class of medications called angiotensin-converting enzyme inhibitors (ACEIs). ACEIs block the substances that constrict the blood vessels and hence more blood and oxygen can reach the heart. Enalapril is therefore used in heart conditions, such as reducing high blood pressure and treating or preventing heart failure.

How to use it?

Enalapril is taken by mouth as tablets, with or without food.
The dosage may be adjusted by your doctor depending on your medical condition and response to medication. The maximum dosage is 40 mg daily for elderly and adults.

High blood pressure
Adult
Initially 5 mg once daily, adjusted according to response. Maintenance dose is 10-20 mg once daily, up to 40 mg in severe cases. If control is inadequate, may be given in 2 divided doses.
Elderly
Initially 2.5 mg once daily, adjust subsequent dose according to response.
Child
Body weight >50 kg: Initially 5 mg once daily, may increase to the maximum dose of 40 mg once daily if necessary.
Body weight 20-50 kg: Initially 2.5 mg once daily, may increase to the maximum dose of 20 mg once daily if necessary.

Heart failure
Adult
Initially 2.5 mg once daily, increase gradually up to 20 mg over 2-4 weeks. Usual maintenance dose is 20 mg daily as a single dose or in 2 divided doses.
Elderly
Initially 2.5 mg once daily, adjust subsequent dose according to response.

What are the side effects of Enalapril?

Common side effects of Enalapril include low blood pressure, angioedema, kidney impairment, dry cough, and elevated potassium levels.

Who should not take Enalapril?

– People allergic to Enalapril, other angiotensin-converting enzyme (ACE) inhibitors, or any formulation ingredient
– Patients with angioedema caused by prior ACE inhibitor use
– Patients on Aliskiren with poor kidney function or diabetes
– Pregnant women and those who are trying to get pregnant

Pharmacist Tips:

– This medication can make you dizzy. Avoid driving or operating machinery until you know how you respond to Enalapril.
– Report to your doctor immediately if you experience symptoms of angioedema (deep swelling around the eyes and lips) when you use this medication.
– This medication may cause dry cough. Tell your doctor if you have a sustained or persistent cough.
– Do not stop the medication abruptly if you have used Enalapril over long periods of time.

Common dosing schedule:
Enalapril is usually taken once daily. It may be taken with or without food.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Enalapril may interact with:
Potassium supplements
– Aliskiren
– Angiotensin II receptor blockers, e.g. Losartan, Telmisartan
– Other medicines for treating hypertension, such as nitrates and calcium channel blockers
– Non-steroidal anti-inflammatory drugs, e.g. Ibuprofen, Ketorolac, Mefenamic Acid

Enalapril can interact with a number of drugs. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Enalapril in Hong Kong?

In Hong Kong, Enalapril is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Enalapril in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.