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Mefenamic acid

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What is Mefenamic acid for?

Mefenamic Acid belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen, which can be used for relieving pain and inflammation. It is indicated for the conditions below:

  • Pain and inflammation in rheumatic disease and other musculoskeletal disorders
  • Mild to moderate pain including dysmenorrhoea (menstrual pain or cramps)
  • Postoperative pain management
  • Headache and migraine
  • Dental pain
  • Fever

How to use it?

Mefenamic Acid can be taken orally and can be used for adults and children older than 12 years old. The usual dosage is 250 to 500 mg 3 to 4 times daily. Mefenamic Acid can be taken with food if it causes indigestion or stomach irritation. Your doctor may also prescribe Mefenamic Acid with a H2 blocker like Famotidine or a proton pump inhibitor like Omeprazole to reduce stomach upset.

What are the side effects of Mefenamic Acid

Like all NSAIDs (non-steroidal anti-inflammatory drugs), the main side effects of Mefenamic Acid are indigestion, nausea, bleeding gastric ulcer, and allergic reaction. With long-term use, Mefenamic Acid can cause kidney injury, bleeding and increase the risk of a cardiovascular event.

Who should not take Mefenamic acid?

  • People who are allergic to Mefenamic acid or any of the formulation component
  • People who are allergic to other NSAIDs
  • People with active gastrointestinal bleeding or a history of it (related to prior NSAID intake), active gastro-intestinal ulcer
  • People with inflammatory bowel disease or severe heart failure

Pharmacist Tips:

  • Do not take more than one product containing NSAIDs at the same time.

Common dosing schedule:
Mefenamic acid can be with food, milk or antacids to minimize stomach distress.


This schedule is for reference only, adjustments may be made according to individual needs.


Some common medications Mefenamic acid may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Mefenamic Acid in Hong Kong?

In Hong Kong, Mefenamic acid is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.


For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Mefenamic acid in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.

Brands in Hong Kong
Available dosage
  • 250mg / 500mg (Capsules)
  • 125mg / 250mg / 500mg (Tablets)
Drug class
Sub class
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Other drugs in same class
Methyl Salicylate
Used for: Pain relief
Chinese name:
Used for: Pain relief, Osteoarthritis, Rheumatoid arthritis, Pain and inflammation in musculoskeletal and joint disorders, Inflammation
Chinese name:
Used for: Inflammation, Rheumatoid arthritis, Gout, Pain, Osteoarthritis, Fever
Chinese name:
Used for: Pain, Inflammation
Chinese name:
Used for: Pain, Inflammation, Fever, Gout
Chinese name: