Medicines & Supplements A to Z > Sertraline


Last updated on 18/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Sertraline


BRAND NAME(S) IN HONG KONG: Setaloft, Setrof, Zoloft

DRUG CLASS: Antidepressant, Selective Serotonin Reuptake Inhibitor (SSRI)

USED FOR: Major depressive disorder, bipolar major depression, obsessive-compulsive disorder, bulimia nervosa, panic disorder

OTHER DRUGS IN THE SAME CLASS: Citalopram, Escitalopram, Fluvoxamine, Fluoxetine, Paroxetine, Vortioxetine

– 50mg, 100mg (tablets)
– 25mg, 50mg, 100mg (capsules)

What is Sertraline for?

Sertraline belongs to a class of medications called selective serotonin reuptake inhibitors (SSRIs). SSRIs are antidepressants which work by allowing a type of chemicals, serotonin, to stay longer in the brain in order to boost mood. Sertraline can be used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), and social phobia.

How to use it?

Sertraline is available as tablets and capsules to be taken by mouth. The usual adult dose is 50- 200 mg daily. If you find Sertraline to be stimulating, we suggest taking it in the morning.

What are the side effects of Sertraline?

Side effects of Sertraline include anxiety, abnormal appetite,insomnia, weakness, impaired concentration, confusion, constipation, diarrhoea, dizziness, gastrointestinal discomfort, bleeding, headache, sexual dysfunction, vomiting, and weight changes.

Who should not take Sertraline?

– People taking monoamine oxidase inhibitors
– People allergic to Sertraline or any formulation component

Pharmacist Tips:

– It often takes a few weeks to see noticeable improvement in your symptoms.
– Do not stop Sertraline abruptly since withdrawal syndrome can occur. 

Common dosing schedule:
Sertraline can be taken with or without food.

Do not drink alcohol as it may worsen your mood or anxiety.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Sertraline may interact with:
– Monoamine oxidase inhibitors, e.g. Selegiline, Rasagiline
– Nonsteroidal anti-inflammatory drugs, Diclofenac, Ibuprofen

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Sertraline in Hong Kong?

In Hong Kong, Sertraline is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Sertraline in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.