Medicines & Supplements A to Z > Metoclopramide

Metoclopramide

Last updated on 19/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Metoclopramide

CHINESE NAME: 甲氧氯普胺

BRAND NAME(S) IN HONG KONG: Metolon, Primperan, Syntomide

DRUG CLASS: Antiemetic; Dopamine antagonist; Prokinetic agent  

USED FOR: Nausea, vomiting, acute migraines

OTHER DRUGS IN THE SAME CLASS: Domperidone

AVAILABLE DOSAGE FORMS:
– 5mg, 10mg (tablets)
– 5mg/5ml (syrups)
– 10mg/2ml (injections)

What is Metoclopramide for?

Metoclopramide works by blocking dopamine and hence accelerates stomach emptying and movement of the upper intestines. It is therefore used to treat conditions affecting the stomach and intestines such as nausea and vomiting, including those induced by chemotherapy or radiotherapy, as a prevention of postoperative nausea and vomiting, acute migraine, and diabetic gastroparesis.

How to use it?

For most uses, the adult dosage is 10 mg up to 3 times daily if taken orally. For acute migraine, the adult dosage is 10 mg for 1 dose as soon as migraine symptoms develop when taken orally, by intramuscular injection, or by slow intravenous injection.

What are the side effects of Metoclopramide?

Common side effects of Metoclopramide include diarrhoea and drowsiness. High doses of Metoclopramide can cause rare side effects like movement problems.

Who should not take Metoclopramide?

– People allergic to Metoclopramide or any formulation component
– People who underwent gastrointestinal surgery within the past 3-4 days
– Patients with history of tardive dyskinesia (a serious movement disorder) related to Metoclopramide, or epilepsy
– Patients with gastrointestinal bleeding, obstruction or perforation

Pharmacist Tips:

– Do not take Metoclopramide continuously for longer than 12 weeks.
– Do not drink alcohol while you are on Metoclopramide.

Common dosing schedule:
You should take Metoclopramide 30 minutes before meal and at bedtime.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Metoclopramide may interact with:
– Anti-Parkinson agents, e.g. Levodopa
Antipsychotics, e.g. Aripiprazole, Olanzapine
Promethazine
– Rivastigmine

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Metoclopramide in Hong Kong?

In Hong Kong, Metoclopramide is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk/

Need more information?

For detailed information about the use of Metoclopramide in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.