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Rasagiline

Last updated on 14/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Rasagiline

CHINESE NAME: 雷莎吉蘭

BRAND NAME(S) IN HONG KONG: Azilect 律莎

DRUG CLASS: Antiparkinsonian agents

SUB CLASS: Monoamine oxidase type B inhibitors

USED FOR: Parkinson’s disease

AVAILABLE DOSAGE FORMS: 1mg (tablets)

What is Rasagiline for?

Rasagiline belongs to a class of medication called Monoamine oxidase type B (MAO-B) inhibitors. It prevents the breakdown of dopamine in the brain to increase dopamine concentration so as to prolong its action. It usually acts as an initial monotherapy in mild Parkinson’s disease, or an adjunct with levodopa/carbidopa in later stages.

How to use it?

Rasagiline can be taken orally as tablets. The usual dose is 1 mg once daily as monotherapy or adjunctive therapy without Levodopa. When used as adjunctive therapy with Levodopa, the initial dose is 0.5 mg once daily, and may increase to 1 mg once daily if needed.

What are the side effects of Rasagiline?

Common side effects of Rasagiline include headache, dyspepsia, arthralgia, dyskinesia, nausea, constipation, and depression

Who should not take Rasagiline?

Concomitant use of Meperidine (Pethidine), TramadolDextromethorphan or tricyclic antidepressants.

Pharmacist Tips:

– Avoid foods and drinks that are high in tyramine, because your blood pressure could get dangerously high. Tyramine-rich foods include most cheese, most alcohol, cured meat (such as salami), sauerkraut, and soy sauce.
– Avoid driving or operating machinery until you know how you respond to Rasagiline as it may cause drowsiness.
– Do not stop taking Rasagiline suddenly as it may cause withdrawal symptoms.

Common dosing schedule:
Rasagiline can be taken with or without food.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Rasagiline may interact with:
Ciprofloxacin
– Antidepressants, e.g. Fluoxetine, Venlafaxine
– Monoamine oxidase inhibitors, e.g. Selegiline
– Antiepileptics, e.g. Carbamazepine
– Cough and cold medicine, e.g. Dextromethorphan
– Sympathomimetics, e.g. Phenylephrine, Xylometazoline

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Rasagiline in Hong Kong?

In Hong Kong, Rasagiline is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Rasagiline in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.