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Milnacipran

Last updated on 23/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Milnacipran

CHINESE NAME: 米那普侖

BRAND NAME(S) IN HONG KONG: Ixel 鬱思樂

DRUG CLASS: Antidepressant; Serotonin / Norepinephrine Reuptake Inhibitor (SNRI)

USED FOR: Depression, fibromyalgia 

OTHER DRUGS IN THE SAME CLASS: Desvenlafaxine, Duloxetine, Venlafaxine

AVAILABLE DOSAGE FORMS: 25mg, 50mg (capsules)

What is Milnacipran for?

Milnacipran belongs to a class of medications called Serotonin / Norepinephrine Reuptake Inhibitor (SNRI). It treats depression by increasing the amount of certain neurotransmitters that correlate with better mood and feelings of satisfaction and calmness. It is also used for the treatment of fibromyalgia (musculoskeletal pain all over the body). 

How to use it?

Milnacipran comes as capsules to be taken by mouth. In the management of depression, the usual oral dose for adults is 50 mg twice daily. 

As for fibromyalgia, your doctor may gradually increase the dose up to 50 mg twice daily. Depending on your response to the medication, your doctor may increase it to 100 mg twice daily. 

What are the side effects of Milnacipran?

Common side effects include headache, dizziness, drowsiness, insomnia, hot flushes, nausea, constipation, muscle weakness, weight loss, and lower blood pressure when standing or sitting (orthostatic hypotension).

Who should not take Milnacipran?

– Anyone who has an allergy to Milnacipran or any other components of the formulation.
– People who are currently taking monoamine oxidase (MAO) inhibitors or within 14 days of discontinuing them

Pharmacist Tips:

– To lower the chance of feeling dizzy, stand up slowly when you have been sitting or lying down.
– It might take a few weeks for Milnacipran to reach its full effect.
– Do not stop taking Milnacipran suddenly, especially if you have been taking it for more than 3 weeks, as you may suffer from withdrawal symptoms, such as nausea and dizziness.
– Antidepressants can induce suicidal thoughts and behaviours in children, adolescents and young adults. Family members and caregivers should monitor closely any changes in their behaviours.  

Common dosing schedule:
Milnacipran can be taken with or without food. Take with food to reduce stomach side effects. 

Do not drink alcohol as it may worsen your mood and depression.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Milnacipran may interact with:
Dextromethorphan
– Monoamine oxidase inhibitors, e.g. Selegiline, Rasagiline
– Nonsteroidal anti-inflammatory drugs, e.g. Diclofenac, Ibuprofen

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Milnacipran in Hong Kong?

In Hong Kong, Milnacipran is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Milnacipran in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.