What is Zoloft for?

Zoloft is a brand product that contains an antidepressant called Sertraline. It is a type of Selective Serotonin Reuptake Inhibitors (SSRI) that works by blocking the uptake of Serotonin and therefore increases its level to produce better mood and the feeling of calm. 


It is used to treat:

  • Major depressive disorder (MDD)
  • Obsessive-compulsive disorder (OCD)
  • Panic disorder (PD)
  • Post-traumatic stress disorder (PTSD)
  • Social anxiety disorder (SAD)
  • Premenstrual dysphoric disorder (PMDD)

How to use it?

The usual initial dose is 25-50 mg daily, and can be titrated in 25-50 mg/day increments once weekly to a maximum dose of 200 mg/day (max 150 mg/day for premenstrual dysphoric disorder).

What are the side effects of Zoloft?

Common side effects of Zoloft include abnormal appetite, sleep disturbance, dizziness, drowsiness, headache, vomiting and weight gain.

Who should not take Zoloft?

  • People who are allergic to Sertraline or any component of the formulation.

Pharmacist Tips:

  • As Zoloft may cause drowsiness, it is recommended to not drive until you know how it can affect you.
  • It might take a few weeks for Zoloft to reach its maximum effect.
  • Do not stop abruptly as it may cause withdrawal symptoms, such as the feeling of anxiety coming back.
  • Avoid alcohol use while taking this medication.

Common dosing schedule: 

  • Zoloft can be with or without food.

This schedule is for reference only, adjustments may be made according to individual needs.


Some common medications Zoloft may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Zoloft in Hong Kong?

In Hong Kong, Zoloft is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.


For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Zoloft in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.

Available dosage
  • 50mg (Tablets)
Drug class
Sub class
Selective Serotonin Reuptake Inhibitors (SSRIs)
Generic Names