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What is Taxotere?
Taxotere is a brand medication that contains Docetaxel, which belongs to a class of mitotic inhibitors. It works by disrupting cell division in cancer cells. It is therefore used in the treatment of breast, oesophageal, lung and other cancers.
How to use it?
Taxotere is available as injections. Your body surface area will be determined in order to calculate the appropriate dose.
For breast cancer, different treatment regimens are used.
As a single therapy: 60-100 mg/m2 once by infusion over 1 hour once every 3 weeks.
Together with Doxorubicin, Capecitabine or Cyclophosphamide: 75 mg/m2 once by infusion over 1 hour once every 3 weeks.
Together with Trastuzumab: 100 mg/m2 once by infusion over 1 hour once every 3 weeks.
For gastric adenocarcinoma, head and neck cancer, non-small cell lung cancer and prostate cancer,
75 mg/m2 by infusion over 1 hour once every 3 weeks in combination with other agents.
Who should not take Taxotere?
- People allergic to any component of Taxotere
- Patients with a neutrophil count <1,500/mm3.
- Patients with severe liver impairment.
- Pregnant or breastfeeding women.
Pharmacist Tips:
- Your doctor will also prescribe a steroid such as Prednisolone, 1 day before Taxotere administration for 3 days to reduce allergic reaction and fluid retention.
Common dosing schedule:
Taxotere is prescribed in institutions by physicians.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Taxotere may interact with:
- Baricitinib
- IBD drugs, e.g. Sulfasalazine, Mesalamine, Balsalazide
- Palifermin
- Tacrolimus
- Vaccines, e.g. BCG, Smallpox and Monkeypox, COVID-19
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
Where to buy Taxotere in Hong Kong?
In Hong Kong, Taxotere is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Taxotere in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
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