It reduces inflammation in the large intestine for treating inflammatory bowel disease, particularly ulcerative colitis. It also slows down the development of rheumatoid arthritis.
Sulfasalazine is available in tablets for oral use. The tablet should be swallowed as a whole. Do not chew or divide the tablet. It should be taken in evenly divided doses, preferably after meals.
Adult and elderly
Upon acute attack, 1-2 g 4 times daily until remission, possibly together with corticosteroids. Upon remission, 2000 mg daily in divided doses. Adjust dose based on the condition, body response and tolerability.
Children above 2 years of age
Upon acute attack, 40-60 mg/kg in divided doses until remission, possibly together with corticosteroids. Upon remission, 20-30 mg/kg daily in divided doses. Adjust dose based on the condition, body response and tolerability.
Adult and elderly
Take 500 mg daily, then step up by 500 mg weekly up to 2-3 g daily in 2-4 divided doses.
Children above 6 years of age
30-50 mg/kg daily in 2 divided doses, up to 2000 mg daily. Adjust dose in case of intolerance.
Common side effects of Sulfasalazine include arthralgia, cough, dizziness, taste alteration, urine abnormalities and gastric discomfort. Myalgia, agranulocytosis and seizure are less likely to occur.
Common dosing schedule:
Sulfasalazine is to be taken in 2-4 evenly divided doses, preferably after meals.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Sulfasalazine may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Sulfasalazine is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Sulfasalazine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
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