Medicines & Supplements A to Z > Combizym


Last updated on 02/08/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Oryz-Aspergillus Enzyme + Pancreatin

CHINESE NAME: 康彼身, 米曲霉酶 + 胰酶

DRUG CLASS: Supplements

SUB CLASS: Enzymes

USED FOR: Enzyme deficiency, Digestion disorders

– 70U, 430U, 7170U, 7400U (tablets)

What is Combizym?

Combizym is a combination therapy that consists of pancreatic enzymes and enzymes extracted from aspergillus oryzae (koji mold). It can be used to replenish enzymes for patients having insufficient exocrine secretion, such as cystic fibrosis and pancreatitis. These patients will have tailor-made dosing from their medical professionals. Pure pancreatic enzyme components are also available as biologics. It can treat dyspepsia (indigestion) for pancreatic insufficiency patients.

How to use it?

Combizym is available as oral tablets which should be taken with or immediately after food and with water.

Enzyme deficiency
Refer to your medical professionals.

Digestion disorder
1-2 tablets daily.

What are the side effects of Combizym?

Common side effects of Combizym include changing blood sugar, stomach ache and changing bowel movements.

Who should not take Combizym?

– Pregnant and breastfeeding women
– Diabetic patients
– People who are allergic to Combizym or any components of the formulation

Pharmacist Tips:

– Taking an excessive dose of Combizym may increase the exposure to side effects.
– Although it is available over the counter, it is advised to consult your medical professional if you have pancreatic insufficiency.
– The effect of Combizym as a supplement is not fully understood.

Common dosing schedule:
1-2 tablets daily taken with or immediately after food and with water.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Combizym may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Combizym in Hong Kong?

In Hong Kong, Combizym is an over-the-counter medicine and can be purchased without a prescription from any retail outlet in Hong Kong. This includes grocery stores, convenience stores, medicine shops, and pharmacies. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Combizym in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.