Calcitriol is an analogue of Vitamin D2, which plays an essential function in calcium absorption and bone growth. It is used to treat various diseases associated with abnormal calcium levels in your body, such as problems of the parathyroid glands and osteoporosis (thinning and weakening of bones) in women after menopause. When applied topically, Calcitriol works by reducing the abnormal proliferation of keratinocytes (a major cell type on the skin surface), induces cell differentiation and restores normal skin growth, therefore, Calcitriol is used topically to treat plaque psoriasis.
Calcitriol is available as capsules or ointment. If you are taking the capsule, swallow it whole with a glass of water. You may take the capsule with or without food. Taking it with food may help to reduce gastrointestinal discomfort. If you are using the ointment, clean and dry the affected area before application, then apply a thin layer and rub in gently and completely. Wash your hands before and after using the medication.
Secondary hyperparathyroidism in chronic kidney disease
Adult
Oral: In patients with moderate to severe chronic kidney disease not yet on dialysis, initially 0.25 mcg daily, which may be increased to 0.5 mcg daily if necessary.
Elderly
Oral: Initiate at lower end of the dosage range.
Postmenopausal osteoporosis
Adult
Oral: 0.25 mcg twice daily.
Renal osteodystrophy
Adult
Oral: In patients undergoing haemodialysis, initially 0.25 mcg daily or every other daily. May be increased by 0.25 mcg at 2-4 week intervals if necessary. Usual dosage range is 0.5-1 mcg daily.
Hypoparathyroidism
Adult
Oral: Initially 0.25 mcg daily given in the morning, which may increase at 2-4 week intervals if necessary.
Elderly
Oral: Initiate at lower end of the dosage range.
Plaque psoriasis
Adult
Topical: Apply onto the affected area twice daily.
Common side effects of Calcitriol include headache, drowsiness, nausea, vomiting, dry mouth, metallic taste, constipation, stomach pain, indigestion, decreased appetite, weight loss, muscle pain, and numbness or tingling sensation in the hands and feet.
Common dosing schedule:
Administer once or twice daily.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Calcitriol may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Calcitriol is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Calcitriol in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
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