Medicines & Supplements A to Z > Indomethacin

Indomethacin

Last updated on 18/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Indomethacin 

CHINESE NAME: 吲哚美辛

BRAND NAME(S) IN HONG KONG: Indocid 恩道式, Indylon, Indecin, Satogesic 濕痛即適

DRUG CLASS: Analgesic, nonopioid; Nonsteroidal anti-inflammatory drug

USED FOR: acute pain including menstrual pain, ankylosing spondylosis, osteoarthritis, rheumatoid arthritis, acute gout 

OTHER DRUGS IN THE SAME CLASS: Aspirin, Ibuprofen, Ketorolac, Mefenamic acid, Naproxen

AVAILABLE DOSAGE FORMS:
– 25mg, 50mg (capsules)
– 100mg (suppositories)

What is Indomethacin for?

Indomethacin belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs) like Diclofenac. This class of drugs can be used to reduce pain and inflammation. It has a wide range of uses depending on its route of administration, including:

Indomethacin tablet and suppository

– Rheumatic disease or other musculoskeletal disorders
– Gout
– Menstrual cramps
– Pain and fever

Indomethacin cream or gel 

– Musculoskeletal and joint pain

How to use it?

Indomethacin can be taken by mouth either in an immediate-release or modified-release capsule, as a suppository, cream and gel. For the modified-release oral tablet of indomethacin, you should swallow whole and do not crush or chew them. All oral forms of indomethacin should be taken with food or milk to avoid stomach upset. The total daily dose of indomethacin should not exceed 200 mg and you should use the lowest dose for the shortest duration possible.

The suggested dosages in adults for different forms of Indomethacin are listed below:

Tablets: Take 25-50 mg 2-3 times per day by mouth.

Suppository: 50-100 mg 1-2 times daily to be inserted rectally

Topical cream or gel: Apply the cream or gel to the painful area 1-4 times daily as needed

What are the side effects of Indomethacin?

Like all NSAIDS (non-steroidal anti-inflammatory drugs), the main side effects of Indomethacin are indigestion, nausea, bleeding gastric ulcer, and allergic reaction. With long-term use Indomethacin can cause kidney injury, bleeding and increase the risk of a cardiovascular event.

Who should not take Indomethacin?

– People with coronary artery bypass graft (CABG) surgery
– People allergic to Indomethacin or any component of the formulation
– People allergic to other NSAIDs
– People with severe liver disease
– People who have experienced bronchospasm, asthma, or rash with NSAIDs

Pharmacist Tips:

You should not take more than one product containing NSAIDs at the same time. 

Common dosing schedule:
You can take Indomethacin with or after food or milk to reduce stomach upset.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Indomethacin may interact with:
– Angiotensin II receptor blockers, e.g. LosartanValsartan
– Angiotensin converting enzyme inhibitors, e.g. Captopril, Lisinopril
– Antiplatelet and anticoagulant drugs e.g. Apixaban, Warfarin
– Other NSAIDs, e.g. Aspirin, Celecoxib, Diclofenac
– Selective serotonin reuptake inhibitors, e.g. Fluoxetine, Sertraline

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Indomethacin in Hong Kong?

In Hong Kong, Indomethacin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk/

Need more information?

For detailed information about the use of Indomethacin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.