Medicines & Supplements A to Z > Ezetimibe


Last updated on 30/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  



BRAND NAME(S) IN HONG KONG: Ezetrol 易降醇, Vytorin 維降醇 (Ezetimibe/Simvastatin), Atozet 易降脂 (Ezetimibe/Atorvastatin)

DRUG CLASS: Lipid-regulating drugs

SUB CLASS: Cholesterol absorption inhibitors

USED FOR: Hyperlipidemia

– 10mg (tablets)
– 10mg/10mg, 10mg/20mg (tablets) (Atozet 易降脂®)
– 10mg/10mg, 10mg/20mg, 10mg/40mg  (tablets) (Vytorin 維降醇®)

What is Ezetimibe for?

Ezetimibe belongs to a class of medications called cholesterol absorption inhibitors which can reduce low-density lipoprotein (LDL, “bad cholesterol”) levels. It is a second-line antihyperlipidemic agent used in Hong Kong, as an adjunct to statin for better blood lipids control. Combination therapy of a statin and Ezetimibe is available in the market now, aiming to reduce frequencies of dosing and improve quality of life for patients, such as Vytorin® (containing Simvastatin) and Atozet® (containing Atorvastatin). The detailed indications include:
– homozygous familial hypercholesterolemia (HoFH)
– homozygous sitosterolemia
– primary hyperlipidemia and mixed hyperlipidemia

How to use it?

Ezetimibe is available in tablets for oral use. The usual dose is 10 mg once daily, usually in combination with a statin.

What are the side effects of Ezetimibe?

Common side effects of Ezetimibe include upper respiratory infection, diarrhea, arthralgia, sinusitis, back pain, and headache.

Who should not take Ezetimibe?

– People allergic to Ezetimibe or any components of the formulation
– Pregnant or breastfeeding women when used with a statin
– Patients with hepatic diseases when used with a statin

Pharmacist Tips:

Lifestyle modification is the first line treatment for hyperlipidemia, which includes a healthy diet, regular exercise and weight management.

Common dosing schedule:
Ezetimibe can be taken with or without food. You may take it at the same time as a statin or Fenofibrate. If you need to take Cholestyramine, administer Ezetimibe ≥ 2 hours before or ≥ 4 hours after Cholestyramine.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Ezetimibe may interact with:
– Fibrates, e.g. Bezafibrate, Gemfibrozil

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Ezetimibe in Hong Kong?

In Hong Kong, Ezetimibe is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Ezetimibe in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.