Medicines & Supplements A to Z > Tienam


Last updated on 02/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Cilastatin + imipenem


DRUG CLASS: Antibiotics

SUB CLASS: Dehydropeptidase inhibitors, Carbapenem

USED FOR: Lower respiratory tract infections, bacterial infections, bacterial meningitis, intra-abdominal infections, skin and soft tissue infections, prevention of surgical infections

– 500/500 mg (injections)

What is Tienam?

Tienam is a brand of product used for various types of bacterial infections. It is effective against aerobic and anaerobic bacterias that are resistant to cephalosporins and aminoglycoside antibiotics. Tienam is also used for the prevention of postoperative infections. Tienam does not work for virus or fungus infections.

How to use it?

Tienam is injected through a needle into a vein or muscle as directed by your doctor. Your doctor will advise you on the dosage and frequency depending on your infection.

Treatment of bacterial infections
Body weight >70 kg: 1-2 g every 6-8 hours.
Body weight >40 kg: 1-2 g every 6-8 hours.
Body weight <40 kg: 15 mg/kg every 6 hours. Maximum dosage is 2 g daily.

Prevention of bacterial infections
1 g on induction of anaesthesia, and 1 g after 3 hours.

What are the side effects of Tienam?

Common side effects of Ertapenem include diarrhoea, nausea and vomiting, thrombophlebitis, and injection site reactions.

Who should not take Tienam?

– People allergic to any component of the formulation.
– People who are allergic to carbapenems.
– People who are allergic to beta-lactams, e.g. Penicillins and Cephalosporins.

Pharmacist Tips:

– If you experience symptoms like skin rash or blistering of skin, report to your doctor immediately.
– Drink plenty of water to replace any lost fluids due to diarrhoea.

Common dosing schedule:
Tienam is commonly administered every 6-8 hours.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Tienam may interact with:
– Anticonvulsants, e.g. Phenobarbital, Phenytoin, Sodium Valproate

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Tienam in Hong Kong?

In Hong Kong, Tienam is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Tienam in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor. 

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.