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Plavix

Last updated on 12/10/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Clopidogrel

CHINESE NAME: 柏域斯

DRUG CLASS: Antiplatelets

SUB CLASS: P2Y12 receptor antagonists, Thienopyridine

USED FOR: Prevention of thromboembolic events, treatment of the acute coronary syndrome

AVAILABLE DOSAGE FORMS:
– 75mg, 300mg (tablets)

What is Plavix for?

Plavix (Clopidogrel) belongs to a class of medications called P2Y12 receptor antagonists. It is an antiplatelet which blocks platelet aggregation and blood clot formation. Plavix is therefore used to prevent thromboembolic events and treat acute coronary syndrome, such as heart attack and stroke.

How to use it?

Plavix can be taken orally as tablets. The initial dose for acute coronary syndrome is 300 or 600 mg once at the time of diagnosis, followed by a maintenance dose of 75 mg once daily.

The usual dose is 75 mg once daily in order to prevent further events. Your doctor will decide how long you need to take Plavix based on your medical history and risk of bleeding.

What are the side effects of Plavix?

Common side effects of Plavix include diarrhoea, gastrointestinal discomfort, bleeding, and skin reactions.

Who should not take Plavix?

– People who are allergic to Clopidogrel or any component of the formulation
– People with active pathological bleeding, such as peptic ulcer

Pharmacist Tips:

– This drug may cause prolonged and excessive bleeding. Inform your doctor or dentist about the use of Clopidogrel before undergoing any surgeries or dental procedures.
– Do not stop taking this medication suddenly even if you feel well, due to the risk of adverse cardiovascular events.
– This drug may not work as well in some people (CYP2C19 poor metabolizers). A genetic test can be done to see if you are one of these people. Talk with your doctor.

Common dosing schedule:
Plavix can be taken with or without food.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Plavix may interact with:
Rifampicin
Warfarin
– Proton-pump inhibitors, e.g. Omeprazole, Esomeprazole
– Opioids, e.g. Morphine, Tramadol
– Nonsteroidal anti-inflammatory drugs (NSAIDs), e.g. Aspirin, Ibuprofen, Naproxen
– Selective serotonin reuptake inhibitors (SSRIs), e.g. Fluoxetine, Paroxetine
– Serotonin norepinephrine reuptake inhibitors (SNRIs), e.g. Venlafaxine 

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Plavix in Hong Kong?

In Hong Kong, Plavix is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Plavix in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.