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Noradrenaline

Last updated on 15/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Noradrenaline

ALTERNATIVE NAME: Norepinephrine

CHINESE NAME: 去甲腎上腺素

BRAND NAME(S) IN HONG KONG: Levophed

DRUG CLASS: Sympathomimetics

SUB CLASS: Alpha agonists, Beta agonists

USED FOR: Acute hypotension

AVAILABLE DOSAGE FORMS: 1mg/mL, 4mg/4mL (injections/infusions)

What is Noradrenaline for?

Noradrenaline belongs to a class of medications called sympathomimetics acting on alpha and beta receptors. Noradrenaline is used for treating acute hypertension.

How to use it?

Noradrenaline is injected or infused through a needle into a vein as directed by your doctor. Your doctor will advise you on the dosage and frequency depending on your blood pressure.

Acute hypotension
Adult
0.4 to 0.8 mg/hr is infused and the dose is increased by 0.05 to 0.1 mcg/kg/min to achieve the target mean arterial blood pressure.
Child
0.05 to 0.1 mcg/kg/min increased up to 2mcg/kg/min to achieve the target mean arterial blood pressure.

What are the side effects of Noradrenaline?

Common side effects of Noradrenaline include bradycardia, arrhythmia, anxiety, temporary headache and dyspnea.

Who should not take Noradrenaline?

People allergic to Noradrenaline or any component of the formulation.

Pharmacist Tips:

Common dosing schedule:
The infusion or injection is continued to maintain a desired blood pressure until deemed stabilized by the doctor.

This schedule is for reference only, adjustments may be made according to individual needs. 

Some common medications Noradrenaline may interact with:
– Alpha-1 antagonists, e.g. Doxazosin, Terazosin
– Ergot derivatives, e.g. Ergotamine, Ergometrine
Linezolid
– Sympathomimetics, e.g. Amphetamines, Pseudoephedrine
– Tricyclic antidepressants, e.g. Imipramine, Nortriptyline

Noradrenaline may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Noradrenaline in Hong Kong?

In Hong Kong, Noradrenaline is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Noradrenaline in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.