Used for: Heartburn, Gastroesophageal Reflux Disease (GERD), Duodenal ulcer, Prevention of NSAID associated ulcers, Helicobacter pylori (H. pylori) eradication, Zollinger-Ellison syndrome
Chinese name:

What is Nexium for?

Nexium is a brand product that contains Esomeprazole, which is a type of proton pump inhibitor. It works by stopping the proton pump to suppress acid production. It is used to treat GERD and peptic ulcers. It also helps with H. pylori eradication by allowing antibiotics to penetrate better to H. pylori.

How to use it?

Nexium is taken orally by mouth. The doses are different depending on its use.

For gastroesophageal reflux disease (GERD), take 20 mg once daily for 4 weeks, and can use it for another 4 weeks if symptoms do not resolve.


For peptic ulcers, take 20 mg twice daily for 7 days.

For H. pylori eradication, take 20-40 mg twice daily (with antibiotics).


For prevention of NSAID-associated ulceration, 20-40 mg once daily.


For Zollinger-Ellison Syndrome, start with 40 mg twice daily. The usual daily dose is 80-160 mg in 2 divided doses.

What are the side effects of Nexium?

Common side effects of Nexium include constipation, dizziness and headache. Long-term use may lead to magnesium deficiency.

Who should not take Nexium?

People who are allergic to esomeprazole or any components of the formulation.

Pharmacist Tips:

  • Magnesium deficiency is possible after long term use. It can cause symptoms like tremors, loss of appetite and muscle cramps. Speak to your healthcare professionals if this occurs.
  • Do not split, crush, or chew with granules. If using granules, mix 10 mg with 15 ml of water, leave 2-3 minutes to thicken and drink within 30 minutes.

Common dosing schedule:
Nexium can be taken with or without food. It should be swallowed whole with a glass of water.


This schedule is for reference only, adjustments may be made according to individual needs.


Some common medications Nexium may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Nexium in Hong Kong?

In Hong Kong, Nexium is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.


For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Nexium in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.

Available dosage
  • 20mg / 40mg (Gastro-Resistant Tablets)
  • 40mg (Injections)
  • 10mg (Sachets)
Drug class
Acid-Reducing Drugs
Sub class
Proton Pump Inhibitors (PPIs)
Generic Names
Other drugs in same class
Used for: Zollinger-Ellison syndrome, Heartburn, Prevention of NSAID associated ulcers, Duodenal ulcer, Helicobacter pylori (H. pylori) eradication, Gastroesophageal Reflux Disease (GERD)
Chinese name:
Used for: Gastroesophageal Reflux Disease (GERD), Zollinger-Ellison syndrome, Peptic Ulcer, Heartburn
Chinese name:
Used for: Zollinger-Ellison syndrome, Heartburn, Duodenal ulcer, Gastroesophageal Reflux Disease (GERD), Prevention of NSAID associated ulcers, Gastric ulcer, Helicobacter pylori (H. pylori) eradication
Chinese name:
Used for: Gastroesophageal Reflux Disease (GERD), Gastric ulcer, Prevention of NSAID associated ulcers, Heartburn, Zollinger-Ellison syndrome, Helicobacter pylori (H. pylori) eradication, Duodenal ulcer
Chinese name: