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Febuxostat

Last updated on 09/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Febuxostat

CHINESE NAME: 非布司他

BRAND NAME(S) IN HONG KONG: Feburic 菲布力

DRUG CLASS: Antigout agents

SUB CLASS: Xanthine oxidase inhibitors

USED FOR: Gout, hyperuricaemia

AVAILABLE DOSAGE FORMS:
– 80 mg, 120 mg (tablets)

What is Febuxostat for?

Febuxostat belongs to a class of medications called antigout agents. It prevents the formation of uric acid in the body, thus reducing the concentration of uric acid in blood plasma. It is used to treat hyperuricaemia and gout.

How to use it?

Febuxostat is available as a tablet which may be taken with or without food.

Hyperuricaemia
Adult
Initially 80 mg once daily. Dose may increase to 120 mg once daily if serum uric acid is greater than 6 mg/100mL after 2-4 weeks of initial dose.

Cancer therapy-induced hyperuricaemia
Adult
120 mg once daily, to be started 2 days before the start of cytotoxic therapy and continued for 7-9 days, according to chemotherapy duration.

What are the side effects of Febuxostat?

Common side effects of Febuxostat include diarrhoea, headache, skin rash, nausea and vomiting, and allergic skin reactions.

Who should not take Febuxostat?

– People allergic to Febuxostat or any component of the formulation.
– Patients who are currently taking Azathioprine or Mercaptopurine.

Pharmacist Tips:

– This medication can make you dizzy. Avoid driving or operating machinery until you know how you respond to Febuxostat.
– If you experience symptoms like severe skin rash, report to your doctor immediately.

Common dosing schedule:
Febuxostat is usually taken once daily.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Febuxostat may interact with:
Azathioprine, Mercaptopurine
Theophylline

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Febuxostat in Hong Kong?

In Hong Kong, Febuxostat is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Febuxostat in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.