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Clobetasol propionate

Last updated on 26/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Clobetasol propionate



BRAND NAME(S) IN HONG KONG: Dermovate 特美膚, Clobex, Cloderm

DRUG CLASS: Corticosteroids

SUB CLASS: Glucocorticoids

USED FOR: Corticosteroid-responsive dermatoses, Plaque psoriasis, Scalp psoriasis

– 0.05% (cream)
– 0.05% (ointment)
– 0.05% (shampoo)
– 0.05% (spray)
– 0.05% (topical solution)

What is Clobetasol propionate for?

Clobetasol propionate belongs to a class of medications called glucocorticoids. It can relieve inflammatory and pruritic manifestations of skin and scalp diseases, including plaque and scalp psoriasis.

How to use it?

Clobetasol propionate can be applied topically on skin as cream, ointment, or spray, while it can also be used on the scalp as shampoo or topical solution. 

For moderate to severe scalp psoriasis:
Shampoo, topical solution:
Apply a thin layer twice daily for up to 2 weeks. Maximum dose is 50 g or 50 ml per week. 

For moderate to severe plaque psoriasis:
Apply by spraying directly onto the affected area twice daily and gently rub into skin, for up to 4 weeks. Maximum dose is 50 g or 59 ml per week. 

For other corticosteroid-responsive dermatoses:
Cream, ointment:
Apply a thin layer twice daily and gently rub into skin for up to 2 weeks. Maximum dose is 50 g or 50 ml per week.

What are the side effects of Clobetasol propionate?

Common side effects of Clobetasol propionate include irritation, burning, pruritus, dryness, and stinging.

Who should not take Clobetasol propionate?

– People who are allergic to Clobetasol, other corticosteroids, or any component of the formulation
– Used for any infections involving the skin

Pharmacist Tips:

– Wash hands before and after use.
– Clean and dry the affected skin well before use.
– Avoid contacts with eyes, face, axillae, or groin.
– Different brands of this drug may be for use in different ages of children. Talk with the doctor before giving this drug to a child.
– Avoid covering with bandages, wraps, or occlusive dressing unless directed otherwise by healthcare providers.
– For shampoo, apply a thin film to dry scalp, massage into affected areas, wait 15 minutes, and then add water, lather, and rinse hair thoroughly.
– For spray, cream, ointment and solution, gently and completely rub into skin after application.

Common dosing schedule:

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Clobetasol propionate may interact with:
– Topical antifungals, e.g. Ketoconazole, Itraconazole

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Clobetasol propionate in Hong Kong?

In Hong Kong, Clobetasol propionate is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Clobetasol propionate in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.