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Valganciclovir

Last updated on 25/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Valganciclovir

CHINESE NAME: 纈更昔洛韋

BRAND NAME(S) IN HONG KONG: Valcyte 克毒癒

DRUG CLASS: Antivirals

SUB CLASS: Viral DNA Polymerase Inhibitors, Guanosine nucleoside analogue

USED FOR: Cytomegalovirus retinitis, Cytomegalovirus infections

AVAILABLE DOSAGE FORMS:
– 50mg/ml (oral solutions)
– 450mg (tablets)

What is Valganciclovir for?

Cytomegalovirus (CMV) is a type of herpes virus. It usually infects salivary glands, but it can affect different parts of the body. Valganciclovir is indicated for treating CMV retinitis, pneumonitis and colitis for immunocompromised patients, such as HIV patients. It blocks the virus from replication by inhibiting DNA polymerase of viruses.

How to use it?

There are solutions and tablets for oral use. It should be administered with meals. The tablets should not be broken, chewed or crushed.

CMV retinitis
Adult with AIDS
900mg twice a day for 21 days. Then 900mg once a day for maintenance. Repeat if retinitis exacerbates. 

Prevention of CMV diseases
Adult receiving organs from CMV-positive people
900mg once daily for 100 days. Start by 10 days after transplantation.

What are the side effects of Valganciclovir?

Common side effects of Valganciclovir include anemia, diarrhea, dizziness, vomiting, nausea and skin reactions.

Who should not take Valganciclovir?

People who are allergic to Ganciclovir, Valganciclovir or any components in the formulations.

Pharmacist Tips:

– Contraception is needed for 30 days and 90 days after treatment for childbearing women and preconception men respectively.
– Complete blood count has to be monitored.
– The tablets should not be broken, chewed or crushed. 

Common dosing schedule:
Valganciclovir should be administered with meals. 

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Valganciclovir may interact with:
– Phenylacetic acids, e.g. Diclofenac, Aceclofenac
– Some antiretrovirals, e.g. Adefovir, Cidofovir
– 2-arylpropionic acid derivatives, e.g. Ibuprofen, Ketoprofen
– Cancer drugs, e.g. Imatinib, Cisplatin
– Immunosuppressants, e.g. Methotrexate, Mercaptopurine

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Valganciclovir in Hong Kong?

In Hong Kong, Valganciclovir is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Valganciclovir in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.