Medicines & Supplements A to Z > Triptorelin

Triptorelin

Last updated on 04/08/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Triptorelin

CHINESE NAME: 曲普瑞林

BRAND NAME(S) IN HONG KONG: Decapeptyl 弟凱得, Diphereline 達菲林

DRUG CLASS: Antineoplastics

SUB CLASS: Gonadotropin-releasing hormone (GnRH) agonists

USED FOR: Cancer hormone therapy, Treatment of prostate cancer, Treatment of breast cancer, Endometriosis, Uterine fibroids, Precocious puberty

AVAILABLE DOSAGE FORMS:
– 0.1 mg, 3.75 mg, 11.25 mg, 22.5 mg (injections)

What is Triptorelin for?

Triptorelin belongs to a class of medications called gonadotropin-releasing hormone (GnRH) agonists. It works by balancing your hormones and treating conditions related to hormone levels in your body. It is used alone or together with surgery or radiation therapy to treat prostate cancer. It is also used in the treatment of early-stage breast cancer with other medications. Endometriosis (a condition in which the tissue that normally lines the inside of the uterus grows in other places), uterine fibroids (abnormal non-cancerous growths in the uterus) and central precocious puberty (premature puberty in children) may also be treated using Triptorelin.

How to use it?

Triptorelin is injected into a muscle or the fatty layer under the skin via a needle as directed by your doctor. Triptorelin is available in two chemical forms, triptorelin acetate and triptorelin embonate, which require different dosages in treating different conditions. Your doctor will advise you on the dosage and frequency depending on your condition.

Palliative treatment of advanced prostate cancer
Adult
As triptorelin pamoate: Inject 3.75 mg once every 4 weeks intramuscularly via the buttock.

Endometriosis
Adult
As triptorelin acetate: Inject 3 mg intramuscularly once every 4 weeks.
As triptorelin pamoate: Inject 11.25 mg intramuscularly every 3 months for a maximum of 6 months (not to be repeated). Start during the first 5 days of the menstrual cycle.

Central precocious puberty
Child over 2 years
As triptorelin pamoate: Inject 11.25 mg intramuscularly once every 3 months.
As triptorelin embonate: Inject 22.5 mg intramuscularly once every 24 weeks.

What are the side effects of Triptorelin?

Common side effects of Triptorelin include headache, dizziness, nausea, stomach discomfort, dry mouth, weight gain, hot flushes, difficulty sleeping, muscle or back pain, breast pain, increased sweating, acne or pimples, and injection site reactions.

Who should not take Triptorelin?

– People allergic to Triptorelin or any component of the formulation
– People allergic to gonadotropin-releasing hormone (GnRH) or its analogues
– Pregnant or breastfeeding women and those who intend to become pregnant
– Women with abnormal vaginal bleeding
– Men with severe osteoporosis

Pharmacist Tips:

– You may need routine tests such as blood tests and bone density tests during Triptorelin treatment.
– Report to your doctor immediately if you experience seizures, tumour flare, chest tightness, chest pain, or difficulty breathing.
– Diabetic patients should monitor symptoms of high blood glucose and report any difficulties with glycemic control.

Common dosing schedule:
Your doctor will advise you on the dosage and frequency depending on your infection.

Some common medications Triptorelin may interact with:
– Antiarrhythmics, e.g. Amiodarone, Quinidine, Disopyramide, Sotalol
– QT prolonging drugs, e.g. Dronedarone, Amisulpride, Pimozide
– Moxifloxacin
– Methadone

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Triptorelin in Hong Kong?

In Hong Kong, Triptorelin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Triptorelin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.