Medicines & Supplements A to Z > Triprolidine


Last updated on 24/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Triprolidine 


BRAND NAME(S) IN HONG KONG: Actifed / Eurofed / Syncofit  (Contains Triprolidine, Pseudoephedrine and others), Actihist (Contains Triprolidine, Pseudoephedrine and Guaifenesin)

DRUG CLASS: Antihistamine (first generation) 

USED FOR: Upper respiratory allergies and pruritic skin disorders

OTHER DRUGS IN THE SAME CLASS:  Brompheniramine, Chlorpheniramine, Cinnarizine, Cyclizine, Cyproheptadine, Diphenhydramine, Dexchlorpheniramine, Hydroxyzine, Promethazine, Pheniramine

AVAILABLE DOSAGE FORMS: 2.5mg (capsules)

What is Triprolidine for?

Triprolidine is a sedating (first generation) antihistamine that can relieve allergic symptoms, such as urticaria, hay fever (rhinitis), and skin disorders in which itch is present. It can also be used in combination with other medications like Pseudoephedrine to treat rhinitis, and coughs and common cold.

How to use it?

Triprolidine is taken orally. The usual dose is 0.25 mg every 4 to 6 hours. The maximum daily dose is 10 mg.

What are the side effects of Triprolidine?

Common side effects of Triprolidine include drowsiness and dizziness, dry mouth, fatigue, headache, nausea, blurred vision, impaired concentration, and abnormal coordination.

Who should not take Triprolidine?

– People allergic to Triprolidine or any formulation component
– People taking sedatives or tranquilizers 

Pharmacist Tips:

– Many antihistamines are available in combination products. Pay attention to the active ingredients when you are choosing over-the-counter medicines for self-treatment. Do not overdose.
– Avoid driving or operating machinery until you know how you respond to Triprolidine.
– See a doctor if your symptoms do not improve after 7 days or if you have a fever.

Common dosing schedule:
You can take Triprolidine with or without food.
Take Triprolidine at night if you become drowsy after taking the medication. (Daytime sedation can be relieved by taking non-drowsy antihistamines as alternatives.) 

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Triprolidine may interact with:
– Antipsychotics, e.g. Aripiprazole, Clozapine
– Hypnotics, such as benzodiazepines (e.g. Lorazepam, Midazolam), Zopiclone, Zolpidem, Chloral Hydrate
– Opioid analgesics, e.g. Morphine, Tramadol 

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Triprolidine in Hong Kong?

In Hong Kong, Triprolidine is an over-the-counter medicine which can be purchased without a prescription from any retail outlet in Hong Kong. This includes grocery stores, convenience stores, medicine shops, and pharmacies. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Triprolidine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.