Medicines & Supplements A to Z > Triazide


Last updated on 12/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Triamterene + Hydrochlorothiazide

CHINESE NAME: 氨苯蝶啶 + 氢氯噻嗪


DRUG CLASS: Antihypertensives, Diuretics

SUB CLASS: Potassium sparing diuretics, Thiazide diuretics

USED FOR: High blood pressure, oedema

AVAILABLE DOSAGE FORMS: 50mg/25mg (tablets)

What is Triazide for?

Triazide is a combination drug consisting of two diuretics, Triamterene and Hydrochlorothiazide. Triamterene belongs to a class of medications called potassium sparing diuretics (which increases potassium level in blood), while Hydrochlorothiazide belongs to a class of medications called Thiazide diuretics (which lowers potassium level in blood). Both drugs work by balancing the amount of salt and water in your body resulting in an increase in the volume of your urine output. Triazide is used to treat high blood pressure and oedema.

How to use it?

Triazide is taken by mouth as tablets. It should be taken with food. Take diuretics before midday (morning or early afternoon) to avoid excessive urination overnight.

High blood pressure
50mg/25mg: Initially 1 tablet daily after the morning meal, adjust subsequent doses according to response. Maximum dosage is 4 tablets daily.

50mg/25mg: Initially 1 tablet twice daily, maintenance dose of 1 tablet daily or 2 tablets on alternate days. Maximum dosage is 4 tablets daily.

What are the side effects of Triazide?

Common side effects of Triazide include headache, loss of appetite, nausea and vomiting, diarrhoea and dizziness. If you are also taking other blood pressure-lowering medications and have intravascular volume depletion, you may also experience postural hypotension, that is your blood pressure falls when you stand up from sitting or lying down.

Who should not take Triazide?

– People allergic to Triazide or any ingredient of the formulation
– People who are allergic to sulfonamide medications
– Patients with anuria (reduced urine production)
– Patients with reduced kidney function or kidney failure

Pharmacist Tips:

– This medication may cause photosensitivity. Use sunscreen and avoid tanning beds and prolonged exposure to sunlight.
– Continue taking Triazide even when you feel well.
– Avoid alcohol while taking this medication.

Common dosing schedule:
Triazide should be taken with food. Do not take Triazide in the late afternoon to avoid going to the toilet while sleeping.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Triazide may interact with:
Potassium supplements
– Angiotensin converting enzyme inhibitors, e.g. Captopril, Lisinopril
– Angiotensin II receptor antagonists, e.g. Losartan, Valsartan
– Non-steroidal anti-inflammatory drugs, e.g. Ibuprofen, Ketorolac, Mefenamic Acid

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Triazide in Hong Kong?

In Hong Kong, Triazide is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Triazide in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.