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Tobramycin

Last updated on 02/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Tobramycin

CHINESE NAME: 妥布黴素、泰百黴素

BRAND NAME(S) IN HONG KONG: Tobrex 點必效, Tobradex 點必舒

DRUG CLASS: Antibiotics

SUB CLASS: Aminoglycosides

USED FOR: Cystic fibrosis, bacterial eye infections, urinary tract infections (UTIs)

AVAILABLE DOSAGE FORMS:
– 0.3% (eye drops)
– 0.3% (eye ointment)
– 40 mg/ml (injections)

What is Tobramycin for?

Tobramycin belongs to a class of medications called aminoglycoside antibiotics. It works by inhibiting the growth of bacteria and is used to treat a wide variety of bacterial infections. It does not work for virus or fungus infections. It is especially effective against species of Pseudomonas and hence is used to treat cystic fibrosis.

Tobramycin is often used in combination with Dexamethasone to treat eye infections.

How to use it?

Tobramycin is available as eye drops and eye ointments to treat eye infections. Wash your hands before and after applying this medication.
Tobramycin is also used in hospital settings as injections to treat cystic fibrosis and other systemic infections.

Bacterial eye infections
Eye: Apply 2 times daily for 6-8 days.

Cystic fibrosis
Adult
Injections: Twice daily, up to 8-10 mg per kg body weight daily in equally divided doses.

Urinary tract infections
Adult
Injections: 2-3 mg per kg body weight for 1 dose.

What are the side effects of Tobramycin?

Common side effects of Tobramycin include tinnitus, diarrhoea and dizziness.
Applying the medication to the eye may cause blurred vision.

Who should not take Tobramycin?

– People allergic to Tobramycin or any component of the formulation.
– People who are allergic to aminoglycosides.
– Patients with myasthenia gravis.

Pharmacist Tips:

– You must complete the entire course of this antibiotic, or else, the infection will not be properly controlled.
– Applying the medication to the eye may cause blurred vision. If affected, do not drive or operate machinery.
– Wearing of contact lenses is not recommended during treatment.
– Since Tobramycin is indicated for infection, remember to clean your hands before using eye products.

Common dosing schedule:
For eye infections, apply 2 times daily.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Tobramycin may interact with:
– Non-steroidal anti-inflammatory drugs, e.g. Ibuprofen, Ketorolac, Mefenamic Acid
– Cephalosporins, e.g. Cephaloridine, Cefazolin, Cefuroxime

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Tobramycin in Hong Kong?

In Hong Kong, Tobramycin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health. 

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Tobramycin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.