Medicines & Supplements A to Z > Ticagrelor


Last updated on 13/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Ticagrelor



DRUG CLASS: Antiplatelets

SUB CLASS: P2Y12 receptor antagonists

USED FOR: Treatment of the acute coronary syndrome, Acute ischemic stroke, Transient ischemic attack, Stable coronary artery disease

AVAILABLE DOSAGE FORMS: 60mg, 90mg (tablets)

What is Ticagrelor for?

Ticagrelor belongs to a class of medications called P2Y12 receptor antagonists. It is an antiplatelet which blocks the platelet from sticking together and blood clot formation. Ticagrelor is therefore indicated for the treatment of acute coronary syndrome (CAS), acute ischemic stroke or transient ischemic attack, as well as the treatment of stable coronary artery disease (CAD), in order to prevent stroke and myocardial infarction.

How to use it?

Ticagrelor is taken orally as tablets. If you have difficulty in swallowing, you may crush the tablets and mix with water for administration.

For treatment of acute coronary syndrome (CAS):
Initial loading dose: 180 mg once
Maintenance dose: 90 mg twice daily for the first year, then 60 mg twice daily thereafter. During maintenance, it has to be in combination with Aspirin (75-100 mg daily).

For minor ischemic stroke (NIHSS score ≤5) or high-risk transient ischemic attack (ABCD2 score ≥4):
Initial loading dose: 180 mg once, with Aspirin (300-325 mg)
Maintenance dose: 90 mg twice daily for up to 30 days. During maintenance, it has to be in combination with Aspirin (75-100 mg daily).

For the treatment of stable coronary artery disease (CAD):
60 mg twice daily, in a combination with Aspirin (75-100mg daily).

What are the side effects of Ticagrelor?

Common side effects of Ticagrelor include bleeding, dyspnea, dizziness, and nausea.

Who should not take Ticagrelor?

– People who are allergic to Ticagrelor or any component of the formulation
– Patients with active pathological bleeding (e.g. peptic ulcer, intracranial hemorrhage), or history of intracranial hemorrhage

Pharmacist Tips:

– This drug may cause you to bleed more easily, so try to avoid injury.
– Do not stop taking this drug suddenly because it may cause serious effects, such as heart attack or stroke.
– This drug has to be taken with Aspirin, which the dose should not exceed 100 mg/day.

Common dosing schedule:
Ticagrelor can be taken with or without food. 

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Ticagrelor may interact with:
– Digoxin
– Lipid-regulating drugs, e.g. Simvastatin, Lovastatin
– Antiepilepsy, e.g. Phenytoin, Carbamazepine
– Antifungals, e.g. Itraconazole, Ketoconazole
– Antibiotics, e.g. Clarithromycin, Erythromycin
– Anticoagulants, e.g. Heparin, Enoxaparin
– Opioid analgesics, e.g. Morphine

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Ticagrelor in Hong Kong?

In Hong Kong, Ticagrelor is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Ticagrelor in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.