Ticagrelor belongs to a class of medications called P2Y12 receptor antagonists. It is an antiplatelet which blocks the platelet from sticking together and blood clot formation.
Ticagrelor is therefore indicated for the treatment of acute coronary syndrome (CAS), acute ischemic stroke or transient ischemic attack, as well as the treatment of stable coronary artery disease (CAD), in order to prevent stroke and myocardial infarction.
Ticagrelor is taken orally as tablets. If you have difficulty in swallowing, you may crush the tablets and mix with water for administration.
For treatment of acute coronary syndrome (CAS):
Initial loading dose: 180 mg once
Maintenance dose: 90 mg twice daily for the first year, then 60 mg twice daily thereafter. During maintenance, it has to be in combination with Aspirin (75-100 mg daily).
For minor ischemic stroke (NIHSS score ≤5) or high-risk transient ischemic attack (ABCD2 score ≥4):
Initial loading dose: 180 mg once, with Aspirin (300-325 mg)
Maintenance dose: 90 mg twice daily for up to 30 days. During maintenance, it has to be in combination with Aspirin (75-100 mg daily).
For the treatment of stable coronary artery disease (CAD):
60 mg twice daily, in a combination with Aspirin (75-100mg daily).
– People who are allergic to Ticagrelor or any component of the formulation
– Patients with active pathological bleeding (e.g. peptic ulcer, intracranial hemorrhage), or history of intracranial hemorrhage
Common dosing schedule:
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Ticagrelor may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Ticagrelor is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Ticagrelor in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
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