Medicines & Supplements A to Z > Sitagliptin


Last updated on 08/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Sitagliptin



DRUG CLASS: Antidiabetic drugs

SUB CLASS: Dipeptidylpeptidase IV (DPP-4) inhibitors

USED FOR: Type 2 diabetes

AVAILABLE DOSAGE FORMS: 25mg, 50mg, 100mg (tablets)

What is Sitagliptin for?

Sitagliptin belongs to a class of medication called dipeptidylpeptidase IV (DPP-4) inhibitors. It works by making the pancreas produce more insulin and less glucagon to control blood sugar level. It is indicated for the treatment of type 2 diabetes mellitus.

How to use it?

Sitagliptin is taken orally as tablets. The usual dose is 100 mg once daily. A lower dose is used in patients with poor kidney function.

What are the side effects of Sitagliptin?

Common side effects of Sitagliptin include headache, upper respiratory infection, or nasopharyngitis. This medication does not cause weight gain.

Who should not take Sitagliptin?

People who are allergic to Sitagliptin or any component of the formulation.

Pharmacist Tips:

– Non-drug management, including diet and exercise, also plays an important role in controlling diabetes.
– Seek medical advice promptly if your body is under stress such as fever, trauma, infection, or surgery, as medication requirements may change.

Common dosing schedule:
Sitagliptin can be taken with or without food.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Sitagliptin may interact with:
– Insulin
– Sulfonylureas, e.g. Glipizide, Gliclazide

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Sitagliptin in Hong Kong?

In Hong Kong, Sitagliptin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Sitagliptin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.