Rivaroxaban belongs to a class of medications called Non-vitamin K antagonist oral anticoagulant (NOAC) or Direct Oral Anticoagulant (DOAC). It is used to treat blood clots, including that in deep veins and in major blood vessels in the lung, and to prevent potential stroke in atrial fibrillation patients (but not for those with abnormal heart valves). It is also used in patients with long-term ischemic heart disease.
Rivaroxaban can be taken orally.
For preventing stroke in atrial fibrillation, the usual dose is 20 mg once daily.
For preventing DVT or PE after surgery, the dose is 10 mg once daily for 35 and 12 days for hip and knee replacement respectively.
For treating DVT or PE, the initial dose is 15 mg twice daily for 21 days; followed by a maintenance dose of 20 mg once daily.
A lower dose is used in patients with poorer kidney function.
The most common side effect is a higher chance of bleeding, for example, easier bruising, black tarry stools (gastrointestinal bleeding), and pink urine (bleeding in the urinary tract), which may lead to anemia.
Common dosing schedule:
Rivaroxaban can be taken with or without food. Take it at the same time on a daily basis. Unlike conventional anticoagulants (e.g. Warfarin), Rivaroxaban has fewer dietary restrictions.
What if I miss a dose?
Rivaroxaban is usually taken once daily. If you remember it within 12 hours, take the missed dose immediately; if it is over 12 hours, skip the missed dose and go back to your normal dosing schedule. Do not take two doses at the same time. Please record the date of the missed dose and tell the doctor in the next follow-up.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Rivaroxaban may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, as dosage adjustments might be needed.
In Hong Kong, Rivaroxaban is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Rivaroxaban in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.