Probenecid belongs to a class of medications called uricosuric agents. It promotes the excretion of uric acid in the urine, thus reducing the concentration of uric acid in blood plasma. It is used to treat hyperuricaemia and gout.
Probenecid is available as a tablet which should be taken with food. Drink plenty of water (2-3 litres per day) to ensure efficient elimination of uric acid via urine.
Hyperuricaemia with gout
Adult
250 mg twice daily for 1 week, followed by 500 mg twice daily thereafter. Increase up to 2 g daily by increments 500 mg every 4 weeks if needed.
Adjunct to antibacterial therapy
Adult
500 mg 4 times daily.
Child over 2 years
Body weight <50 kg: Initially, 25 mg/kg body weight in 4 divided doses, followed by 40 mg/kg body weight in 4 divided doses.
Common dosing schedule:
Probenecid is usually administered every 12 hours in the treatment of hyperuricaemia and gout.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Probenecid may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Probenecid is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Probenecid in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
Healthy Matters is Hong Kong’s leading health resource. Our mission is to help you make better health decisions and take control of your health.
Our team of experts is committed to producing reliable health content that is accurate, engaging and relevant, to cover your health & wellness journey from prevention to treatment.
Whether you are looking for trusted information on health conditions, wellbeing or looking for the right doctor or service in Hong Kong, we’re here to help!
Your health matters. Begin your health journey with Healthy Matters today!