What is Pristiq for?

Pristiq is a brand product that contains an antidepressant called Desvenlafaxine. It is a type of Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) that works by blocking the uptake of serotonin and norepinephrine to produce better mood and the feeling of calm. It is indicated for major depression.

How to use it?

Pristiq is taken orally. The usual dose is 50 mg once daily, and can be increased to 100 mg if not effective after 6 weeks.

It can be taken with or without food. Swallow the whole tablet. Do not chew, break, crush or dissolve.

What are the side effects of Pristiq?

Common side effects of Pristiq include dizziness, drowsiness, dry mouth, weight loss, and sleep disturbance.

Who should not take Pristiq?

People who are allergic to Desvenlafaxine, Venlafaxine or any component of the formulation.

Pharmacist Tips:

  • Slowly stand up after sitting or lying down for a long time to avoid dizziness.
  • As Pristiq may cause drowsiness, it is recommended to not drive until you know how it can affect you.
  • It might take a few weeks for Pristiq to reach its maximum effect.
  • Do not stop abruptly as it may cause withdrawal symptoms, such as the feeling of anxiety coming back.
  • The inert tablet shell may appear in stool. It is normal and the active medication has already been absorbed.
  • Avoid alcohol use while using this medication.

Common dosing schedule:
Pristiq can be taken with or without food. It should ​​be administered at approximately the same time each day.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Pristiq may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Pristiq in Hong Kong?

In Hong Kong, Pristiq is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.


For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Pristiq in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.

Available dosage
  • 25mg / 50mg / 100mg (Extended-Release Tablets)
Drug class
Sub class
Serotonin and norepinephrine reuptake inhibitors (SNRIs)
Generic Names
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