Prednisone belongs to the class of medications called glucocorticoids or steroid hormones like Hydrocortisone. It mainly works by reducing inflammation with a wide range of uses such as treating moderate to severe rheumatoid arthritis, acute asthma, exacerbations of chronic obstructive pulmonary disease, allergies and idiopathic thrombocytopenic purpura.
Prednisone is taken by mouth usually in the form of regular tablets. Regular release tablets are typically taken once daily in the morning. Low-dose modified-release tablets (Lodotra) are taken at bedtime and may be useful in people who have morning stiffness from rheumatoid arthritis. It is advised to take Prednisone with food or milk to reduce gastrointestinal upset. Modified-release tablets should be swallowed whole, and should not be crushed or chewed. You should take Prednisone as directed by your doctor. Long-term treatment with Prednisone is usually tapered slowly. Do not stop taking Prednisone without professional advice.
Prednisone has a wide variety of dosages and uses. The usual adult dose range may vary from 1 to 50 mg per day. Your doctor will prescribe the appropriate dose for your medical condition. Because regular prednisone tablets are only available in 5 mg tablets, it is normal to take multiple tablets per day. For example, if your dose is 30 mg daily, will need to take six 5 mg Prednisone tablets.
When Prednisone is taken by mouth for long-term use, it can have side effects such as anxiety, cataracts, cognitive impairment, fat redistribution (moon face and buffalo hump), fluid retention, gastrointestinal discomfort, headache, impaired wound healing, high blood pressure, increased risk of infection, menstrual cycle irregularities, and osteoporosis.
– People allergic to Prednisone or any other component of the formulation.
– Patients with systemic fungal infections.
– Report signs of new or worsening infections to your doctor or pharmacist.
– After long-term use of this drug, contact your doctor or pharmacist if you notice fatigue, weight gain, or thinning of skin that bruises easily.
– Do not discontinue Prednisone abruptly on your own, discuss with your doctor or pharmacist before stopping.
– Long term use of Prednisone may slow down growth in children and teenagers.
Common dosing schedule:
Take Prednisone with or after food or milk to reduce stomach discomfort.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Prednisone may interact with:
– Antacids, e.g. Aluminium hydroxide
– Antidiabetic agents, e.g. Metformin
– Anticoagulants, e.g. Warfarin
– Hormonal contraceptives
– Non-steroidal anti-inflammatory drugs (NSAIDs), e.g.Celecoxib, Diclofenac, Ibuprofen
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Prednisone is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Prednisone in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.