Medicines & Supplements A to Z > Prednisolone

Prednisolone

Last updated on 18/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAMES: Prednisolone

CHINESE NAME: 培尼皮質醇

BRAND NAME(S) IN HONG KONG: Econopred Plus, Minims Prednisolone Sodium Phosphate, Panafcortelone, Predsol Retention Enema, Redipred 

DRUG CLASS:  Corticosteroid / glucocorticoid; Anti-inflammatory agent

USED FOR: Asthma, chronic obstructive pulmonary disease, inflammatory joint diseases, inflammatory eye or ear disorders, inflammatory bowel disease 

OTHER DRUGS IN THE SAME CLASS: Dexamethasone, Hydrocortisone, Prednisone

AVAILABLE DOSAGE FORMS:
– 0.12%, 1% (eye drops)
– 0.10% (cream)
– 0.10% (ointment)
– 4mg, 5mg, 10mg (tablets)
– 40mg, 125mg, 250mg, 500mg (injections)

What is Prednisolone for?

Prednisolone belongs to a class of medications called glucocorticoids or steroid hormones. It mainly works by reducing inflammation with a wide range of indications, including: 

– Respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD)
– Inflammatory joint diseases (e.g. gout)
– Allergic and inflammatory disorders
– Inflammatory eye disorders
– Allergic and inflammatory conditions of the ear
– Inflammatory bowel disease such as Crohn’s disease and ulcerative colitis
– A component of cancer treatment

How to use it?

For allergic and inflammatory disorders

Oral 

Adult
Usual range is 5-60 mg daily and may be given as daily divided doses, daily single dose, a double dose on alternate days. Dosage is individualised according to the disease and your response. 

For inflammatory eye disorders

To the eyes  

Adult / Child
As 1% Prednisolone acetate suspension: Instill 1-2 drops into the conjunctival sac 2-4 times daily, may increase to 2 drops every hour during the initial 24-48 hours;

As 0.5% Prednisolone sodium phosphate solution: Instill 1-2 drops every 1-2 hours until control is achieved.

For allergic and inflammatory conditions of the ear

To the ears 

Adult
As 0.5% Prednisolone Na phosphate solution: Instill 2 or 3 drops into the ear 2 or 3 every hour until control is achieved. The frequency of administration depends on your response and the treatment needs to be discontinued if there is no response within 7 days of treatment.

For Crohn’s disease, ulcerative colitis

Rectal 

Adult
For rectal and rectosigmoidal disease: 

As enema: 1 enema at bedtime for 2-4 weeks. 

As suppository: Remove the wrapper and Insert 1 suppository at bedtime and 1 suppository in the morning after defecation.

What are the side effects of Prednisolone?

When used as a cream or ointment, minimise the period of time you use Prednisolone as long-term use can cause skin thinning. When Prednisolone is taken by mouth for long-term use, it can have more serious side effects such as anxiety, cataracts, cognitive impairment, fat redistribution (moon face and buffalo hump), fluid retention, gastrointestinal discomfort, headache, impaired wound healing, high blood pressure, increased risk of infection, menstrual cycle irregularities, and osteoporosis.

Who should not take Prednisolone?

– People allergic to Prednisolone or any other components of the formulation
– Patients with systemic fungal infections

Pharmacist Tips:

– Report signs of new or worsening infections to your doctor or pharmacist.
– After long-term use of this drug, contact your doctor or pharmacist if you notice fatigue, weight gain, or thinning of skin that bruises easily.
– If you are using eye ointment, your vision can be blurred for a few minutes. You should shake the suspension well before use to ensure accurate dosing.
– Do not discontinue Prednisolone abruptly on your own, discuss with your doctor or pharmacist before stopping.
– Long term use of Prednisolone may slow down growth in children and teenagers. 

Common dosing schedule:
Take Prednisolone with or after food or milk to reduce stomach discomfort. 

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Prednisolone may interact with:
– Antacids, e.g. Aluminium hydroxide
– Antidiabetic agents, e.g. Metformin
– Anticoagulants, e.g. Warfarin
– Echinacea
– Hormonal contraceptives
– Non-steroidal anti-inflammatory drugs (NSAIDs), e.g.CelecoxibDiclofenac, Ibuprofen 

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Prednisolone in Hong Kong?

In Hong Kong, Prednisolone is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk/

Need more information?

For detailed information about the use of Prednisolone in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.