Medicines & Supplements A to Z > Piperacillin


Last updated on 06/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Piperacillin


BRAND NAME(S) IN HONG KONG: Pipracil, Tazocin 特治星

DRUG CLASS: Antibiotics

SUB CLASS: Penicillins

USED FOR: Bacterial infections, gonorrhoea, prevention of surgical infections

AVAILABLE DOSAGE FORMS: 2 g (injections)

What is Piperacillin for?

Piperacillin belongs to a class of medications called penicillins. It kills bacteria by interrupting the integrity of bacterial cell walls. Piperacillin is used to treat a wide range of bacterial infections. Piperacillin does not work for virus or fungus infections.

Piperacillin is often used in combination with Tazobactam for the treatment of pneumonia and other infections.

How to use it?

Piperacillin is injected through a needle into a vein or muscle as directed by your doctor. Your doctor will advise you on the dosage and frequency depending on your infection.

Uncomplicated gonorrhoea
2 g as a single dose in combination with 1 g oral dose of Probenecid given before the injection.

Severe infections
200-300 mg/kg body weight daily in divided doses. At least 16 mg daily, and a maximum dosage of 24 g daily.

Mild or uncomplicated infections
100-125 mg/kg body weight daily.

Prevention of surgical infections
2 g just before the procedure, followed by at least 2 doses of 2 g every 4-6 hours within 24 hours of the procedure.

What are the side effects of Piperacillin?

Common side effects of Piperacillin include diarrhoea, nausea and vomiting, and allergic skin reactions.

Who should not take Piperacillin?

Anyone who has an allergy to Piperacillin or other penicillins.

Pharmacist Tips:

– Antibiotics like Piperacillin may reduce the effectiveness of oral contraceptives. Consider using another form of contraception while taking Amoxicillin.
– You must complete the entire course of this antibiotic, or else, the infection will not be properly controlled.

Common dosing schedule:
Your doctor will advise you on the dosage and frequency depending on your condition.

Some common medications Piperacillin may interact with:
Oral contraceptives, e.g. Desogestrel, Drospirenone, Levonorgestrel

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Piperacillin in Hong Kong?

In Hong Kong, Piperacillin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Piperacillin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.