Medicines & Supplements A to Z > Parecoxib

Parecoxib

Last updated on 24/03/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Parecoxib 

CHINESE NAME: 帕瑞昔布

BRAND NAME(S) IN HONG KONG: Dynastat 

DRUG CLASS: Analgesic, non-opioid; Non-steroidal anti-inflammatory drug (NSAID), COX-2 selective

USED FOR: Postoperative pain 

OTHER DRUGS IN THE SAME CLASS: Celecoxib, Etoricoxib

What is Parecoxib for?

Parecoxib belongs to a class of medications called non-steroidal anti-inflammatory drugs like Ibuprofen. It is used for the short-term management of acute postoperative pain.

How to use it?

Parecoxib is given by intravenous or deep intramuscular injection. 

Adult
Start with 40 mg, then 20-40 mg every 6-12 hours. The maximum daily dose is 80 mg for 3 days. 

Elderly (body weight ≤ 50 kg)
Start with 20 mg. The maximum daily dose is 40 mg.  

What are the side effects of Parecoxib?

Like all NSAIDS, the main side effects of Etoricoxib are indigestion, nausea, bleeding gastric ulcer, and allergic reaction. With long-term use, Etoricoxib can cause kidney injury, bleeding and increase the risk of a cardiovascular event.

Who should not take Parecoxib?

– Anyone who has allergic reactions after taking Aspirin or other NSAIDs. Discuss with your doctor if you have ever got symptoms such as hives and flushing after taking Aspirin or other NSAIDs to see if you could change to another drug instead
– Anyone who has an allergy to Parecoxib or any other components of the product
– People with heart failure, or other cerebrovascular diseases
– People with active gastrointestinal bleeding or ulceration

Pharmacist Tips:

Many NSAIDs are available in Hong Kong and should not be used while taking Parecoxib.

Common dosing schedule:
No specific arrangement regarding meals.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Parecoxib may interact with:
– Angiotensin II receptor blockers, e.g. Valsartan, Losartan
– Angiotensin converting enzyme inhibitors, e.g. Captopril, Lisinopril
– Antiplatelet and anticoagulant drugs e.g. Apixaban, Warfarin 
– Bisphosphonates, e.g. Alendronate
– Other NSAIDs, e.g. Aspirin, Diclofenac, Celecoxib
– Corticosteroids, e.g. Dexamethasone, Fluticasone
– Selective serotonin reuptake inhibitors, e.g. Fluoxetine, Sertraline

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Parecoxib in Hong Kong?

In Hong Kong, Parecoxib is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at http://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Pravastatin in children, pregnancy, and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.