> Western Medicines > Paliperidone


Used for: Schizophrenia
Chinese name:

What is Paliperidone for?

Paliperidone belongs to a class of medications called atypical antipsychotics. It works by balancing the chemicals in your brain and hence restores normal mood, mind, and behaviour. Paliperidone is therefore used to treat schizophrenia.

How to use it?

Paliperidone is available as an extended-release tablet, which is taken by mouth with or without food. Take consistently either always with food or always without food. Swallow whole, and do not divide, chew or crush the tablet.


Alternatively, Paliperidone can also be injected through a needle into a muscle as directed by your doctor. Your doctor will advise you on the dosage and frequency depending on your condition.


Oral extended-release tablet: Initially 6 mg once daily in the morning. Adjust in increments of 3 mg over at least 5 days if necessary. Usual dose range is 3-12 mg daily.
Extended-release intramuscular injection: Initially 150 mg on day 1, then 100 mg after a week. Administer the third dose 1 month after the second initiation dose. Monthly maintenance dose is 75 mg. Usual dose range is 25-150 mg.

What are the side effects of Paliperidone?

Common side effects of Paliperidone include anxiety, abnormal appetite, cough, diarrhoea, fever, gastrointestinal discomfort, allergic skin reactions, agitation, amenorrhoea, constipation, dizziness, drowsiness, dry mouth, erectile dysfunction, insomnia, parkinsonism, seizure, tremor and vomiting.

Who should not take Paliperidone?

People allergic to Paliperidone or any component of the formulation.

Pharmacist Tips:

  • This medication may cause sedation. Avoid driving or operating machinery until you know how you respond to Paliperidone.
  • Do not consume alcohol while on this medication.

Common dosing schedule:
Paliperidone is taken once daily. It may be taken by mouth with or without food. Take consistently either always with food or always without food.


This schedule is for reference only, adjustments may be made according to individual needs.


Some common medications Paliperidone may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Paliperidone in Hong Kong?

In Hong Kong, Paliperidone is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.


For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Paliperidone in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.

Brands in Hong Kong
Invega Trinza
Invega Sustenna
Available dosage
  • 175mg / 263mg / 350mg / 525mg (Extended-Release Injectable Suspension)
  • 50mg / 75mg / 100mg / 150mg (Extended-Release Injectable Suspension)
  • 3mg / 6mg / 9mg (Extended-Release Tablets)
Drug class
Sub class
Atypical Antipsychotics
Other drugs in same class
Used for: Schizophrenia
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Used for: Schizophrenia
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