Oxaliplatin belongs to a class of medications called alkylating agents. It stops cells from replicating and dividing by interfering with their nucleic acid function. This kills cells and inhibits the growth of malignant tumours. Oxaliplatin is used to treat cancers of the large intestine (colon) and rectum. It is used together with other anticancer medications, Fluorouracil and Folinic acid, to treat stage 3 colon cancer after surgical removal of tumour, or metastatic colon cancer (tumour that has spread to other parts of the body).
Oxaliplatin is injected into a vein as directed by your doctor. This process takes many hours, and you will need to rest in the hospital ward or clinic when you are on the medicine drip. Before you start using Oxaliplatin, you may be given other medicines beforehand to prevent or lessen the side effects of Oxaliplatin. The dosage of Oxaliplatin is calculated by your doctor based on your total body surface area. Your doctor will advise you on the dosage and frequency depending on your condition.
Metastatic colorectal cancer (In combination with Fluorouracil or Folinic acid)
65-85 mg per m2 body surface area given every 2 weeks for 12 cycles.
Stage III colon cancer (as adjunct therapy, in combination with Fluorouracil or Folinic acid)
75-85 mg per m2 body surface area given every 2 weeks for 12 cycles.
Common dosing schedule:
Your doctor will advise you on the dosing schedule depending on your condition.
Some common medications Oxaliplatin may interact with:
Oxaliplatin may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Oxaliplatin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Oxaliplatin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.