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Nimodipine

Last updated on 15/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Nimodipine

CHINESE NAME: 莫尼地平

BRAND NAME(S) IN HONG KONG: Nimotop 尼膜同, Nortolan

DRUG CLASS: Vasodilators

SUB CLASS: Calcium Channel Blockers

USED FOR: Subarachnoid hemorrhage

AVAILABLE DOSAGE FORMS:
– 30 mg (tablets)
– 0.2mg/mL, 10mg/50mL (injections)

What is Nimodipine for?

Nimodipine belongs to a class of medication called calcium channel blockers, used to relax the muscles in blood vessels and lead to vasodilation. It is used to treat subarachnoid hemorrhage within 96 hours.

How to use it?

Nimodipine can be taken orally as tablets on an empty stomach at least 1 hour before or 2 hours after meals, or injected through the veins for, at maximum, 21 consecutive days. Swallow the tablets whole with a glass of water. Do not crush or chew it.

Subarachnoid hemorrhage
Adult
Oral: 60 mg every 4 hours for 21 consecutive days or until transitioned to injection. For those with hepatic impairment, the dose may be halved.
Intravenous injection: At an initial rate of 0.5 or 1 mg/hour for 2 hours, increased to 2 mg/hour for 5 to 14 days.

What are the side effects of Nimodipine?

Common side effects of Nimodipine include decreased blood pressure, bradycardia, headache and nausea.

Who should not take Nimodipine?

– People who are allergic to Nimodipine or any component of the formulation
– People who are also taking strong CYP3A4 inhibitors
– People who are also taking phenobarbital, phenytoin, carbamazepine, or rifampin
– Patients with active or recent myocardial infarction or unstable angina

Pharmacist Tips:

– Administer the tablets on an empty stomach at least 1 hour before or 2 hours after meals
– Do not crush or chew the tablets
– Do not administer the oral and intravenous formulation at the same time

Common dosing schedule:
The intravenous formulation is prescribed for 2 hours for 5 to 14 days depending on the physician’s recommendation.

The oral formulation is taken every 4 hours for 21 consecutive days or until it is switched to IV therapy. For example, it can be taken at 8 (breakfast), 12 (lunch), 16 (tea time), 20 (after dinner).

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Nimodipine may interact with:
– Aprepitant
– Dantrolene
– Fluoxetine
– Pholcodine

Nimodipine may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Nimodipine in Hong Kong?

In Hong Kong, Nimodipine is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Nimodipine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.