Medicines & Supplements A to Z > Milrinone


Last updated on 15/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  




DRUG CLASS: Vasodilators

SUB CLASS: Phosphodiesterase inhibitors

USED FOR: Heart failure with reduced ejection fraction

AVAILABLE DOSAGE FORMS: 1mg/mL (injections)

What is Milrinone for?

Milrinone is a vasodilator belonging to a class of medications called phosphodiesterase inhibitors to relax the muscle in blood vessels and dilate them reserved for decompensated patients.

How to use it?

Milrinone is injected intravenously in combination with standard heart failure therapies at an initial rate of 0.125 mcg/kg/min titrated up to 0.75 mcg/kg/min until the lowest effective dose is attained. 

For those who are at least moderately renally impaired, the initial rate and maximum rate is halved.

Your doctor will advise you on the dosage and frequency depending on your heart failure.

What are the side effects of Milrinone?

Common side effects of Milrinone are mainly cardiovascular, including ventricular arrhythmia, supraventricular cardiac arrhythmia, hypotension, angina pectoris, chest pain and headache.

Who should not take Milrinone?

People who are allergic to Milrinone or any component of the formulation.

Pharmacist Tips:

Common dosing schedule:
Milrinone is prescribed by physicians until the ejection fraction is restored to a desired level.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Milrinone may interact with:
– Anagrelide
– Riociguat
– Diuretics, e.g. Furosemide, Bumetanide, Torasemide

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Milrinone in Hong Kong?

In Hong Kong, Milrinone is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at

Need more information?

For detailed information about the use of Milrinone in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.