Midodrine belongs to a class of medications called sympathomimetics acting on alpha receptors. Midodrine is used for treating postural hypotension.
Midodrine is taken through the oral route. It may be taken with or without food. Taking it with food may help to reduce gastrointestinal discomfort.
Adult and elderly
The initial dose is 2.5 mg 3 times daily during daytime hours. The dose is titrated based on response and tolerability up to a usual maximum dose of 10 mg 3 times daily.
Common side effects of Midodrine include bradycardia, supine hypertension, goosebumps, itchiness, dysuria and paresthesia.
Common dosing schedule:
Midodrine is taken three times daily during daytime hours at an upright position. It may be taken with food to minimise gastrointestinal irritation.
Avoid taking the tablets after the evening meal or within 4 hours of bedtime to prevent supine hypertension. An example of the regimen is that doses may be given in 3 to 4-hour intervals. It can be taken when you just wake up, then at 12 and finally at 4.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Midodrine may interact with:
Midodrine may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Midodrine is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Midodrine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
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