> Western Medicines > Mianserin


Used for: Depression
Chinese name:

What is Mianserin for?

Mianserin belongs to a class of medication called tricyclic (or tetracyclic) antidepressants. It is indicated for the treatment of depressive disorder.

How to use it?

Mianserin can be taken orally as tablets. The usual daily dose is 30-40 mg/day in divided doses or as a single dose at bedtime. You may gradually increase the dose to 30-120 mg as the maintenance dose. If needed and recommended by professionals, divided doses up to 200 mg/day are acceptable. For elderly patients, the initial dose should not exceed 30 mg/day, with a lower than normal maintenance dose.


Swallow the tablets whole. Do not crush or chew it.

What are the side effects of Mianserin?

Common side effects of Mianserin include dizziness, dry mouth, drowsiness, fatigue, constipation, or headache.

Who should not take Mianserin?

  • People who are allergic to Mianserin or any component of the formulation
  • Patients with mania, severe liver problems
  • Patients taking monoamine oxidase inhibitors, such as Selegiline, Rasagiline

Pharmacist Tips:

  • Avoid driving or operating machinery as one of the most common side effects is drowsiness, especially during the first few days of treatment.
  • Patients should not drink alcohol during the treatment.
  • Blood tests are recommended during the treatment. Monitor and report for any signs of infection, such as fever and sore throat.

Common dosing schedule:
Mianserin should be administered between meals in divided doses or as a single bedtime dose. Bedtime single dosing may be preferred over divided doses in elderly patients.


This schedule is for reference only, adjustments may be made according to individual needs.


Some common medications Mianserin may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Mianserin in Hong Kong?

In Hong Kong, Mianserin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.


For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Mianserin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.

Available dosage
  • 10mg / 30mg (Tablets)
Drug class
Sub class
Tricyclic Antidepressants (TCAs)
Other drugs in same class
Used for: Major depression, Nocturnal enuresis in children
Chinese name:
Used for: Depression
Chinese name:
Used for: Depression
Chinese name:
Used for: Depression
Chinese name: