Medicines & Supplements A to Z > Methycobal


Last updated on 19/10/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Mecobalamin / Methylcobalamin / Vitamin B12



SUB CLASS: Vitamin (water soluble)

USED FOR: Vitamin B12 deficiency, Peripheral neuropathy

– 500μg (tablets)
– 500mcg/ml (injections)

What is Methycobal for?

Methycobal is a brand product that contains Methylcobalamin, which is the active form of vitamin B12 (a water-soluble vitamin). It has an important role in normal metabolic function, neuronal protection, and red blood cell production. Vitamin B12 deficiency usually occurs in patients with malabsorption problems or with a strict vegetarian diet, which may lead to some forms of anemia.

Methycobal tablet is indicated for the treatment of peripheral neuropathies, while Methycobal injection is used to treat both peripheral neuropathies and megaloblastic anemia (due to vitamin B12 deficiency).

How to use it?

Methycobal is available as tablets or injections. 

For peripheral neuropathy
Tablets: 500 mcg three times daily.
Injection: 500 mcg three times weekly

For megaloblastic anemia due to vitamin B12 deficiency
Injection: 500 mcg three times weekly; after around 2 months, you may adjust the dose to 500 mcg every 1-3 months for maintenance therapy.

What are the side effects of Methycobal?

Methycobal is generally safe and has no significant side effects. In rare cases, Methycobal may cause an upset stomach.

Who should not take Methycobal?

People who are allergic to any derivative of vitamin B12, D-mannitol, or any component of the formulation.

Pharmacist Tips:

– Vitamin B12 is mainly found in animal products. Therefore, vegan diets may result in vitamin B12 deficiency and may require supplementation.
– It is always highly recommended to get nutrients like Vitamin B12 from natural sources first. Foods rich in vitamin B12 are beef, eggs, clams, and milk, etc.
– Avoid alcohol use as heavy drinking may reduce vitamin B12 absorption.

Common dosing schedule:
Methycobal can be taken with or without food.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Methycobal may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Methycobal in Hong Kong?

In Hong Kong, Methycobal tablets are an over-the-counter medicine and can be purchased without a prescription from any retail outlet in Hong Kong. This includes grocery stores, convenience stores, medicine shops, and pharmacies. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

In Hong Kong, Methycobal injection is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at


Need more information?

For detailed information about the use of Methycobal in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.