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Lyrica

Last updated on 08/10/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Pregabalin

CHINESE NAME: 利痛抑

DRUG CLASS: Anticonvulsant

SUB CLASS: Calcium Channel Blockers

USED FOR: Neuropathic pain (including diabetic peripheral neuropathy, spinal cord injury and postherpetic neuralgia), Fibromyalgia, Partial seizure 

AVAILABLE DOSAGE FORMS:
– 25mg, 50mg, 75mg, 100mg, 150mg, 200mg, 300mg (capsules)

What is Lyrica for?

Lyrica is a brand product that contains Pregabalin, which is a type of anticonvulsant. It is thought to block the pain signals sent out from the damaged nerves to treat neuropathic pain. It can also be used for partial seizure and fibromyalgia.

How to use it?

Lyrica is available as capsules and is taken orally. Listed below are the indications and the dosages, in which dose should be adjusted in adult patients with reduced renal function.

For neuropathic pain (diabetic peripheral neuropathy)
Begin with 50 mg three times daily, then titrate up to 100 mg three times daily (maximum) within 1 week based on efficacy and tolerability. 

For neuropathic pain (postherpetic neuralgia)
Begin with 150 mg daily in divided doses (i.e. 75 mg twice daily or 50 mg 3 times daily), then titrate up to 300 mg daily in divided doses within 1 week based on efficacy and tolerability. After 2-4 weeks, it may further increase up to a maximum of 600 mg/day.

For neuropathic pain (spinal cord injury)
Begin with 75 mg twice daily, then titrate up to 150 mg twice daily within 1 week based on efficacy and tolerability. After 2-3 weeks, it may further increase up to a maximum of 600 mg/day.

For fibromyalgia
Begin with 75 mg twice daily, then titrate up to 150 mg twice daily within 1 week based on efficacy and tolerability. After 2-3 weeks, it may further increase up to a maximum of 600 mg/day.

As adjunctive therapy for partial seizures
Begin with 150 mg daily in 2-3 divided doses. It may increase based on response and tolerability at weekly intervals up to a maximum dose of 600 mg/day.

What are the side effects of Lyrica?

The common side effects of Lyrica include swelling in arms or legs, drowsiness, constipation, dry mouth, and weight gain.

Who should not take Lyrica?

– People who are allergic to Pregabalin or any components of the formulation
– People who are pregnant or breastfeeding are not recommended to take Lyrica

Pharmacist Tips:

– As Lyrica may cause drowsiness, it is recommended to not drive until you know how it can affect you.
– Avoid alcohol use while using this medication.
– Do not stop taking this medication suddenly, as adverse effects are enhanced such as increased seizure frequency.

Common dosing schedule:
Lyrica can be taken with or without food.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Lyrica may interact with:
– Opioid analgesics, e.g. Tramadol, Fentanyl, Oxycodone
– Angiotensin-converting enzyme inhibitors, e.g. Captopril, Lisinopril

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Lyrica in Hong Kong?

In Hong Kong, Lyrica is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Lyrica in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.