Medicines & Supplements A to Z > Leuprorelin
Last updated on 04/08/2021.
GENERIC NAME: Leuprorelin
ALTERNATIVE NAME: Leuprolide
CHINESE NAME: 亮丙瑞林
BRAND NAME(S) IN HONG KONG: Lorelin 樂利宜, Enantone 安怡泰, Eligard
DRUG CLASS: Antineoplastics
SUB CLASS: Gonadotropin-releasing hormone (GnRH) agonists
USED FOR: Cancer hormone therapy, Treatment of prostate cancer, Treatment of breast cancer, Endometriosis, Uterine fibroids, Precocious puberty
AVAILABLE DOSAGE FORMS:
– 3.75 mg, 7.5 mg, 22.5 mg, 45mg (injections)
What is Leuprorelin for?
Leuprorelin belongs to a class of medications called gonadotropin-releasing hormone (GnRH) agonists. It works by balancing your hormones and treating conditions related to hormone levels in your body. It is used to treat breast cancer, advanced prostate cancer, endometriosis (a condition in which the tissue that normally lines the inside of the uterus grows in other places), uterine fibroids (abnormal non-cancerous growths in the uterus) and precocious puberty (premature puberty in children).
How to use it?
Leuprorelin is injected into a muscle or the fatty layer under the skin via a needle as directed by your doctor. The usual dosage is 11.25 mg once every 3 months or 3.75 mg once every month. Your doctor will advise you on the dosage and frequency depending on your condition.
Palliative treatment of advanced prostate cancer
Inject 3.75 mg once every month or 11.25 mg once every 3 months.
Inject 3.75 mg once every month or 11.25 mg once every 3 months for a maximum of 6 months (not to be repeated). Start during the first 5 days of the menstrual cycle.
Inject 3.75 mg once every month or 11.25 mg once every 3 months for a maximum of 6 months. Start during the first 5 days of the menstrual cycle. Treatment duration is usually up to 3 months.
Injection is given every 4 weeks. Discontinue before age 11 for females and age 12 for males.
What are the side effects of Leuprorelin?
Common side effects of Leuprorelin include headache, dizziness, nausea, stomach discomfort, weight gain, hot flushes, difficulty sleeping, muscle or back pain, breast pain, increased sweating, acne or pimples, and injection site reactions.
Who should not take Leuprorelin?
– People allergic to Leuprorelin or any component of the formulation
– People allergic to gonadotropin-releasing hormone (GnRH) or its analogues
– People with abnormal vaginal bleeding
– Pregnant or breastfeeding women and those who intend to become pregnant
– You may need routine tests, such as blood tests, during Leuprorelin treatment.
– Report to your doctor immediately if you experience seizures, tumour flare, chest tightness, chest pain, or difficulty breathing.
– Diabetic patients should monitor symptoms of high blood glucose and report any difficulties with glycemic control.
Common dosing schedule:
Your doctor will advise you on the dosage and frequency depending on your infection.
Some common medications Leuprorelin may interact with:
– Antiarrhythmics, e.g. Amiodarone, Quinidine, Disopyramide, Sotalol
– QT prolonging drugs, e.g. Dronedarone, Amisulpride, Pimozide
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
Where to buy Leuprorelin in Hong Kong?
In Hong Kong, Leuprorelin is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Leuprorelin in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.