Medicines & Supplements A to Z > Leflunomide
Last updated on 04/08/2021.
GENERIC NAME: Leflunomide
CHINESE NAME: 來氟米特
BRAND NAME(S) IN HONG KONG: Arava 艾炎寧
DRUG CLASS: Immunomodulatory drugs
SUB CLASS: Disease-Modifying Anti-Rheumatic Drugs, Antimetabolites
USED FOR: Rheumatoid arthritis
AVAILABLE DOSAGE FORMS:
– 10mg, 20mg, 100mg (tablets)
What is Leflunomide for?
Leflunomide, which is a disease-modifying anti-rheumatic drug (DMARD), belongs to a class of medications called antimetabolites. It inhibits the synthesis of a substance responsible for causing inflammation to treat rheumatoid arthritis.
How to use it?
Leflunomide is taken orally as tablets. The usual dose is 100 mg once daily for 3-5 days, followed by 20 mg once daily, which can be reduced to 10 mg if not tolerated.
What are the side effects of Leflunomide?
Common side effects of Leflunomide include diarrhea, alopecia, nausea, headache, and rash.
Who should not take Leflunomide?
– People who are allergic to Leflunomide or any component of the formulation
– People with severe liver impairment
– Pregnant women
– Concomitant use of Teriflunomide
– Use effective contraception during treatment and before drug elimination procedures to avoid pregnancy or fathering a child.
– This drug may cause serious liver problems. Report any symptoms immediately such as fatigue, abdominal pain, loss of appetite, itching, bruising, and yellow skin or eyes.
– This drug may make you more susceptible to infections. Seek medical help immediately if you have symptoms such as fever and sore throat.
Common dosing schedule:
Leflunomide can be taken with or without food.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Leflunomide may interact with:
– Live vaccine
– Lipid-regulating drugs, e.g. Rosuvastatin, Atorvastatin
– Oral contraceptives, e.g. Levonorgestrel, Ethinylestradiol
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
Where to buy Leflunomide in Hong Kong?
In Hong Kong, Leflunomide is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Leflunomide in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.