Medicines & Supplements A to Z > Lansoprazole

Lansoprazole

Last updated on 25/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Lansoprazole

CHINESE NAME: 蘭索拉唑

BRAND NAME(S) IN HONG KONG: Takepron 泰克胃通

DRUG CLASS: Gastrointestinal Drugs

SUB CLASS: Proton Pump Inhibitors

USED FOR: Gastroesophageal Reflux Disease (GERD), Peptic Ulcers, Zollinger-Ellison syndrome

AVAILABLE DOSAGE FORMS:
– 15mg, 30mg (orodispersible tablets)
– 30mg, 60mg (capsules)

What is Lansoprazole for?

It strongly inhibits the secretion of gastric acid in the stomach by blocking the proton pumps in stomach cells. It acts as a first line drug for peptic ulcers, especially the one caused by H. pylori. It can also be prescribed for prophylaxis of gastric ulcer when patients need to take drugs that cause gastrointestinal bleeding (such as Aspirin).

How to use it?

Lansoprazole is available in orodispersible tablets and capsules that can be taken orally. Take it 30-60 minutes before a meal. Do not crush, chew or break the capsules or tablets.

H. pylori-associated peptic ulcer
Adult
30mg twice daily, together with triple therapy (amoxicillin, clarithromycin) for 4 weeks. Step up to quadruple therapy (bismuth, metronidazole, tetracycline) for 8 weeks if failed.

Peptic ulcer
Adult
30mg daily

Zollinger-Ellison Syndrome
Adult
60mg daily, can be adjusted to 120mg or more in 2 doses.

Gastroesophageal Reflux Disease (GERD)
Adult
30mg daily every morning for 4 weeks, continue for 4 more weeks if not recovered fully. 

What are the side effects of Lansoprazole?

Common side effects of Lansoprazole include abdominal pain, GI discomfort, dry mouth, fatigue and headache. Painful joints (arthralgia), painful muscles (myalgia), edema and enlarged breasts for men (gynecomastia) are unlikely to occur.

Who should not take Lansoprazole?

– Pregnant and breastfeeding women.
– People who are allergic to lansoprazole or any component in the formulation.

Pharmacist Tips:

– Lansoprazole is available in delayed-release and immediate-release formulations, which can have very different regimens and dosing schedules.
– There is a risk of osteoporosis for Lansoprazole users in advanced age. Make sure to take enough calcium and vitamin D.
– Lansoprazole may mask the alarming symptoms of gastric cancer. It should be eliminated before treatment.
– Do not crush, chew or break the capsules or tablets.
– If the capsules cannot be swallowed, choose orodispersible tablets or mix the content of capsules with 60mL of orange, apple or tomato juice. 

Common dosing schedule:
Take 30mg twice daily. Take it 30-60 minutes before a meal. 

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Lansoprazole may interact with:
– Antivirals, e.g. Atazanavir, Ritonavir
Dipyridamole
– Azole antifungals, e.g. Itraconazole, Ketoconazole
Methotrexate

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Lansoprazole in Hong Kong?

In Hong Kong, Lansoprazole is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Lansoprazole in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.