Infliximab, which is a monoclonal antibody and biologics Disease-Modifying Anti-Rheumatic Drug (DMARDs), belongs to a class of medications called Tumour Necrosis Factor inhibitors. It works by inhibiting a substance in the body to reduce inflammation and weaken the immune system. It is used to treat Crohn’s disease, moderate-to-severe rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis.
Infliximab is administered through intravenous infusion. Prior to administration, you may be premedicated with antihistamines, Paracetamol, and/or corticosteroids to prevent infusion-related reactions (such as dizziness, nausea, fever, vomiting).
For Crohn’s disease in patients ≥6 years of age:
5 mg/kg at 0, 2, and 6 weeks, followed by 5 mg/kg every 8 weeks thereafter.
For moderate to severe rheumatoid arthritis:
3 mg/kg at 0, 2, and 6 weeks, followed by 3 mg/kg every 8 weeks thereafter. It has to be in combination with Methotrexate.
For plaque psoriasis:
5 mg/kg at 0, 2, and 6 weeks, followed by 5 mg/kg every 8 weeks thereafter.
For psoriatic arthritis:
5 mg/kg at 0, 2, and 6 weeks, followed by 5 mg/kg every 8 weeks thereafter. It can be used with or without Methotrexate.
For ulcerative colitis in patients ≥6 years of age:
5 mg/kg at 0, 2, and 6 weeks, followed by 5 mg/kg every 8 weeks thereafter.
For ankylosing spondylitis:
5 mg/kg at 0, 2, and 6 weeks, followed by 5 mg/kg every 6 weeks thereafter.
Common dosing schedule:
N/A.
This schedule is for reference only, adjustments may be made according to individual needs.
Some common medications Infliximab may interact with:
Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.
In Hong Kong, Infliximab is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.
For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk
Need more information?
For detailed information about the use of Infliximab in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.
Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.
Healthy Matters is Hong Kong’s leading health resource. Our mission is to help you make better health decisions and take control of your health.
Our team of experts is committed to producing reliable health content that is accurate, engaging and relevant, to cover your health & wellness journey from prevention to treatment.
Whether you are looking for trusted information on health conditions, wellbeing or looking for the right doctor or service in Hong Kong, we’re here to help!
Your health matters. Begin your health journey with Healthy Matters today!