> Western Medicines > Glipizide


Used for: Type 2 diabetes
Chinese name:

What is Glipizide for?

Glipizide belongs to a class of medication called sulfonylureas. It can stimulate the release of insulin from your body and sensitize your body to insulin. Therefore, it is used for the treatment of type 2 diabetes mellitus.

How to use it?

Glipizide can be taken orally as conventional tablets and extended-release tablets. In Hong Kong, the only brand for extended-release formulation is Glucotrol XL®.


Conventional tablets:
The usual initial dose is 5 mg once daily administered 30 minutes before breakfast, and may be increased in 2.5-5 mg increments no more frequently than every few days. If a once-daily dose does not provide adequate glycemic control, dividing the daily dose into 2 doses, given 30 minutes before breakfast and 30 minutes before the evening meal. The maximum dose is 20 mg/day, in which doses >15 mg/day should generally be administered in 2 divided doses.


Extended-release tablets:
The usual initial dose is 5 mg once daily with breakfast or the first meal of the day, and may be increased in 5-10 mg increments once weekly. The maximum dose is 20 mg/day. Swallow the modified-release tablets whole with a glass of water. Do not crush or chew it.

What are the side effects of Glipizide?

The common side effects of Glipizide include dizziness, diarrhea, nausea, hypoglycemia, or headache.

Who should not take Glipizide?

  • People who are allergic to Glipizide, other sulfonylureas or sulfonamides, or any component of the formulation
  • Patients with type 1 diabetes, severe renal or hepatic impairment

Pharmacist Tips:

  • Non-drug management, including diet and exercise, also plays an important role in controlling both diabetes.
  • Drinking alcohol is not advisable during treatment.
  • As hypoglycemia can occur, symptoms should be aware, such as drowsiness, confusion, cool pale skin, excessive hunger, or fast heartbeat. If you recognize some of these signs of the drop in blood sugar, immediately eat or drink something containing sugar and notify your doctor without delay.

Common dosing schedule:
For conventional tablets, Glipizide should be administered 30 minutes before breakfast (or the first main meal of the day).


For extended-release tablets, Glipizide should be administered with breakfast (or the first main meal of the day).


This schedule is for reference only, adjustments may be made according to individual needs.


Some common medications Glipizide may interact with:

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Glipizide in Hong Kong?

In Hong Kong, Glipizide is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.


For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Glipizide in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.

Brands in Hong Kong
Glucotrol XL
Available dosage
  • 5mg (Tablets)
  • 5mg (Extended-Release Tablets)
Drug class
Antidiabetic Drugs
Sub class
Other drugs in same class
Used for: Type 2 diabetes
Chinese name: