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Galantamine

Last updated on 15/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions  |   Tips  |   Where To Buy  

GENERIC NAME: Galantamine

CHINESE NAME: 加蘭他敏

BRAND NAME(S) IN HONG KONG: Reminyl 利憶靈

DRUG CLASS: Central nervous system agents

SUB CLASS: Acetylcholinesterase inhibitors

USED FOR: Alzheimer disease

AVAILABLE DOSAGE FORMS:
– 4 mg (orodispersible tablets)
– 8 mg, 16 mg, 24 mg (prolonged-release capsules)

What is Galantamine for?

Galantamine belongs to a class of medications called central nervous system agents inhibiting an enzyme acetylcholinesterase to slow down the breakdown of a neurotransmitter acetylcholine. Galantamine is used for treating Alzheimer disease.

How to use it?

Galantamine is taken orally as orodispersible tablets, which prevents patients from spitting it out, with breakfast and dinner and prolonged-release capsules with breakfast.

Mild to moderate Alzheimer disease
Adult and elderly
Orodispersible tablets: The initial dose is 4 mg twice daily for 4 weeks, increased by 4 mg twice daily up to 12 mg twice daily for at least 4 weeks.
Prolonged-release tablets: The initial dose is 8 mg once daily for 4 weeks, increased by 8 mg once daily up to 24 mg once daily for at least 4 weeks.

What are the side effects of Galantamine?

Common side effects of Galantamine include nausea and vomiting, decreased appetite, diarrhoea, abdominal pain, headache and dizziness.

Who should not take Galantamine?

People allergic to Galantamine, other tertiary alkaloids or any component of the formulation.

Pharmacist Tips:

– There are usually behavioural symptoms like anxiety and anger in Alzheimer’s patients. Identify the triggers and avoid them.
– Change the environment to make Alzheimer’s patients feel more comfortable and secure if needed.
– Avoid arguing about facts with Alzheimer’s patients.

Common dosing schedule:
Orodispersible tablets are taken with breakfast and dinner and prolonged-release capsules are taken with breakfast.

This schedule is for reference only, adjustments may be made according to individual needs. 

Some common medications Galantamine may interact with:
– Antipsychotic agents, e.g. Risperidone, Quetiapine, Clozapine
– Beta-blockers, e.g. Bisoprolol, Metoprolol, Propranolol
– Anticholinergic agents, e.g. Atropine, Benztropine, Benzhexol
– Cholinergic agonists, e.g. Pilocarpine, Donepezil, Parathion
– Corticosteroids, e.g. Hydrocortisone, Dexamethasone, Prednisolone

Galantamine may interact with many other medications. Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Galantamine in Hong Kong?

In Hong Kong, Galantamine is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Galantamine in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.