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Flutamide

Last updated on 13/07/2021.

Overview   |   Dosage   |    Side Effects   |   Precautions   |   Tips   |   Where To Buy  

GENERIC NAME: Flutamide

CHINESE NAME: 氟他胺

BRAND NAME(S) IN HONG KONG: Flutan

DRUG CLASS: Antiandrogens, Antineoplastics

SUB CLASS: Hormone antagonists

USED FOR: Treatment of prostate cancer

AVAILABLE DOSAGE FORMS:
– 250mg (tablets)

What is Flutamide for?

Flutamide belongs to a class of medications called hormone antagonists. It works by inhibiting a hormone in the body to stop the growth and spread of prostate cancer cells. It is indicated for the treatment of local (stage B2 and C) and metastatic prostate cancer, in combination with a GnRH agonist.

How to use it?

Flutamide is taken orally as tablets. The usual dose is 250 mg three times daily in combination with a GnRH analogue, such as Goserelin.

For locally confined prostate cancer, Flutamide should start 8 weeks prior to initiating radiation therapy and continue during radiation therapy. 

For metastatic prostate cancer, Flutamide should continue until disease progression.

What are the side effects of Flutamide?

Common side effects of Flutamide include hot flashes, decreased libido, diarrhea, vomiting, impotence, and galactorrhea.

Who should not take Flutamide?

– People who are allergic to Flutamide or any component of the formulation
– Patients with severe hepatic impairment.

Pharmacist Tips:

This drug may cause serious liver problems. Report any symptoms immediately such as fatigue, abdominal pain, loss of appetite, itching, bruising, and yellow skin or eyes. 

Common dosing schedule:
Flutamide can be taken with or without food. Doses should be administered every 8 hours.

This schedule is for reference only, adjustments may be made according to individual needs.

Some common medications Flutamide may interact with:
– Warfarin

Please notify your doctor or pharmacist if you are taking the above medication, dosage adjustments might be needed.

Where to buy Flutamide in Hong Kong?

In Hong Kong, Flutamide is a prescription only medicine, and requires a prescription from a doctor to be purchased in a pharmacy. It can also be obtained from doctors. To find a pharmacy near you, refer to the list of pharmacies (“Authorized Sellers of Poisons”) from the Hong Kong Department of Health.

For more information about drug names and ingredients, you can visit Hong Kong’s Drug Office at https://www.drugoffice.gov.hk

Need more information?

For detailed information about the use of Flutamide in children, pregnancy and breastfeeding, and for questions about drug interactions, please check with your pharmacist or doctor.

Disclaimer: our goal is to provide you with the most relevant drug information and common dosage for Hong Kong. This information does not constitute medical advice. For specific treatment recommendations and advice, always discuss with your doctor or pharmacist, and follow the instructions included with your specific medicine.